OBJECTIVE: The purpose of this study was to evaluate the results and complications of standard ePTFE versus stretch ePTFE AV fistulas. DESIGN: Prospective randomised trial. SETTING: University Hospital. MATERIALS: During a 2-year period 37 patients received 17 stretch and 20 standard ePTFE graft AV fistulas. CHIEF OUTCOME MEASURES: Patients were evaluated for the occurrence of complications and graft patency. Regular Duplex scans were performed to detect stenoses in the fistula circuit. MAIN RESULTS:Thrombotic events occurred in 40% of the standard ePTFE grafts, compared to 12% of the stretch ePTFE prostheses (p < 0.001). The incidence of puncture complications was similar in both groups. The cumulative primary patency rate in the stretch ePTFE group was significantly higher compared to the standard ePTFE group (1-year patency rates of 59% and 29%, respectively; p < 0.01). No differences in the duration of puncture site bleeding were observed. Duplex scanning showed a significantly greater number of stenoses in the standard ePTFE grafts. CONCLUSIONS: The new stretch ePTFE prosthesis has better primary patency rates and less stenoses due to intimal hyperplasia as compared to standard ePTFE grafts.
RCT Entities:
OBJECTIVE: The purpose of this study was to evaluate the results and complications of standard ePTFE versus stretch ePTFEAV fistulas. DESIGN: Prospective randomised trial. SETTING: University Hospital. MATERIALS: During a 2-year period 37 patients received 17 stretch and 20 standard ePTFE graft AV fistulas. CHIEF OUTCOME MEASURES: Patients were evaluated for the occurrence of complications and graft patency. Regular Duplex scans were performed to detect stenoses in the fistula circuit. MAIN RESULTS:Thrombotic events occurred in 40% of the standard ePTFE grafts, compared to 12% of the stretch ePTFE prostheses (p < 0.001). The incidence of puncture complications was similar in both groups. The cumulative primary patency rate in the stretch ePTFE group was significantly higher compared to the standard ePTFE group (1-year patency rates of 59% and 29%, respectively; p < 0.01). No differences in the duration of puncture site bleeding were observed. Duplex scanning showed a significantly greater number of stenoses in the standard ePTFE grafts. CONCLUSIONS: The new stretch ePTFE prosthesis has better primary patency rates and less stenoses due to intimal hyperplasia as compared to standard ePTFE grafts.
Authors: Taku Kokubo; Noriyuki Ishikawa; Hisashi Uchida; Sara E Chasnoff; Xun Xie; Suresh Mathew; Keith A Hruska; Eric T Choi Journal: J Am Soc Nephrol Date: 2009-05-07 Impact factor: 10.121
Authors: Jennifer M MacRae; Christine Dipchand; Matthew Oliver; Louise Moist; Charmaine Lok; Edward Clark; Swapnil Hiremath; Joanne Kappel; Mercedeh Kiaii; Rick Luscombe; Lisa M Miller Journal: Can J Kidney Health Dis Date: 2016-09-27
Authors: Grace Pohan; Pascale Chevallier; Deirdre E J Anderson; John W Tse; Yuan Yao; Matthew W Hagen; Diego Mantovani; Monica T Hinds; Evelyn K F Yim Journal: Front Bioeng Biotechnol Date: 2019-05-22