Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Enantioselective determination of chiral 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) in human milk samples by multidimensional gas chromatography/electron capture detection and by mass spectrometry.

Literature DB >> 7620847

Enantioselective determination of chiral 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) in human milk samples by multidimensional gas chromatography/electron capture detection and by mass spectrometry.

Abstract

The enantiomeric ratio (ER) of the chiral polychlorinated biphenyl (PCB) 132 (2,2',3,3',4,6'-hexachlorobiphenyl) was determined in human milk samples. The enantiomers were separated by multidimensional gas chromatography (MDGC), using different achiral columns for pre-separation and a Chirasil-Dex column for enantiomer separation, and quantified by electron-capture detection (ECD) and by mass spectrometry (MS/SIM). The determined enantiomeric ratios varied between 0.45-0.85 (enantiomeric excess: 38-8%).

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1995 PMID： 7620847 DOI： 10.1016/0045-6535(95)00085-m

Source DB: PubMed Journal: Chemosphere ISSN： 0045-6535 Impact factor: 7.086

Keyword Cloud
Cited

6 in total

1. Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice.

Authors: I Kania-Korwel; K C Hornbuckle; L W Robertson; H-J Lehmler
Journal: Food Chem Toxicol Date: 2007-09-15 Impact factor: 6.023

6. Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity.

Authors: Eric Uwimana; Brianna Cagle; Coby Yeung; Xueshu Li; Eric V Patterson; Jonathan A Doorn; Hans-Joachim Lehmler
Journal: Toxicol Sci Date: 2019-07-03 Impact factor: 4.849

6 in total

Enantioselective determination of chiral 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) in human milk samples by multidimensional gas chromatography/electron capture detection and by mass spectrometry.

1. Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice.

Review 2. Toxicokinetics of chiral polychlorinated biphenyls across different species--a review.

Review 3. Chiral polychlorinated biphenyl transport, metabolism, and distribution: a review.

4. Distribution of chiral PCBs in selected tissues in the laboratory rat.

Review 5. Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review.

6. Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity.