| Literature DB >> 7620463 |
H van Keulen1, W L Homan, S L Erlandsen, E L Jarroll.
Abstract
The nucleotide sequence of the 16S rRNA gene and the space DNA region was determined for Giardia duodenalis, obtained from humans in The Netherlands (AMC-4) and Washington State (CM). These rDNA sequences differ from other G. duodenalis isolates (Portland-1 and BRIS/83/HEPU/ 106) both of which have virtually identical rDNA sequences. The most characteristic feature was found close to the 5' end of the 16S rRNA. The Portland-1 -Bris/83/HEPU/ 106 type has GCG in position 22-24, while AMC-4 and CM have AUC in this position. These two sequences, present in an otherwise conserved region of the 16S rRNA, are "signature" sequences, which divide Giardia isolates into two different groups.Entities:
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Year: 1995 PMID： 7620463 DOI： 10.1111/j.1550-7408.1995.tb01600.x
Source DB: PubMed Journal: J Eukaryot Microbiol ISSN： 1066-5234 Impact factor: 3.346