LTP is accompanied by commensurate enhancement of auditory-evoked responses in a fear conditioning circuit.

Transmission of auditory information from the medial geniculate body to the lateral nucleus of the amygdala is believed to be involved in the conditioning of fear responses to acoustic stimuli. This pathway exhibits LTP of electrically evoked field potentials after high frequency stimulation of the medial geniculate body. High frequency stimulation of the medial geniculate body also results in a long-lasting potentiation of a field potential in the lateral amygdala elicited by a naturally transduced acoustic stimulus. This demonstrates that natural information processing can make use of the physiological mechanisms set in motion by LTP induction.