Literature DB >> 7619514

Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons.

C Vicario-Abejón1, K K Johe, T G Hazel, D Collazo, R D McKay.   

Abstract

Restrictions in neuronal fate occur during the transition from a multipotential to a postmitotic cell. This and later steps in neuronal differentiation are determined by extracellular signals. We report that basic fibroblast growth factor is mitogenic for stem cells and is a differentiation factor for calbindin-expressing hippocampal neurons. The neurotrophin NT-3 is a differentiation factor for the same neurons but does not affect proliferation. NT-3 and brain-derived neurotrophic factor promote the maturation of neurons derived from stem cells that have been grown in vitro. These results define functions for basic fibroblast growth factor and neurotrophins in the differentiation processes that direct a multipotential stem cell to a specific neuronal fate.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7619514     DOI： 10.1016/0896-6273(95)90068-3

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  66 in total

1.  Astroglial differentiation of cortical precursor cells triggered by activation of the cAMP-dependent signaling pathway.

Authors:  M F McManus; L C Chen; I Vallejo; M Vallejo
Journal:  J Neurosci       Date:  1999-10-15       Impact factor: 6.167

Review 2.  Neurotrophins: roles in neuronal development and function.

Authors:  E J Huang; L F Reichardt
Journal:  Annu Rev Neurosci       Date:  2001       Impact factor: 12.449

3.  FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice.

Authors:  Shinichi Yoshimura; Tetsuyuki Teramoto; Michael J Whalen; Michael C Irizarry; Yasushi Takagi; Jianhua Qiu; Jun Harada; Christian Waeber; Xandra O Breakefield; Michael A Moskowitz
Journal:  J Clin Invest       Date:  2003-10       Impact factor: 14.808

4.  Multiple factors control the proliferation and differentiation of rat early embryonic (day 9) neuroepithelial cells.

Authors:  R Li; W Q Gao; J P Mather
Journal:  Endocrine       Date:  1996-10       Impact factor: 3.633

5.  Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.

Authors:  Koos E Hovinga; Fumiko Shimizu; Rong Wang; Georgia Panagiotakos; Maartje Van Der Heijden; Hamideh Moayedpardazi; Ana Sofia Correia; Denis Soulet; Tamara Major; Jayanthi Menon; Viviane Tabar
Journal:  Stem Cells       Date:  2010-06       Impact factor: 6.277

6.  Myoepithelial Cells: Their Origin and Function in Lacrimal Gland Morphogenesis, Homeostasis, and Repair.

Authors:  Helen P Makarenkova; Darlene A Dartt
Journal:  Curr Mol Biol Rep       Date:  2015-07-10

Review 7.  Cell death in the nervous system: lessons from insulin and insulin-like growth factors.

Authors:  Isabel Varela-Nieto; Enrique J de la Rosa; Ana I Valenciano; Yolanda León
Journal:  Mol Neurobiol       Date:  2003-08       Impact factor: 5.590

Review 8.  The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain.

Authors:  G Mudò; A Bonomo; V Di Liberto; M Frinchi; K Fuxe; Natale Belluardo
Journal:  J Neural Transm (Vienna)       Date:  2009-03-17       Impact factor: 3.575

9.  Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells.

Authors:  X Yang; C L Cepko
Journal:  J Neurosci       Date:  1996-10-01       Impact factor: 6.167

10.  Basic fibroblast growth factor increases functional L-type Ca2+ channels in fetal rat hippocampal neurons: implications for neurite morphogenesis in vitro.

Authors:  Y Shitaka; N Matsuki; H Saito; H Katsuki
Journal:  J Neurosci       Date:  1996-10-15       Impact factor: 6.167
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.