Literature DB >> 761838

Jejunal lysozyme activity and the Paneth cell in coeliac disease.

M Ward, A Ferguson, M A Eastwood.   

Abstract

The jejunal mucosa of patients with coeliac disease contains significantly fewer Paneth cells (PCC) per crypt (p less than 0.001) and tissue lysozyme activity (JLA) P less than 0.001) when compared with a group of subjects with normal jejunal mucosa. Neither PCC nor JLA return to normal with complete clinical recovery and otherwise complete histological recovery on a gluten free diet. There is a significant linear correlation between JLA and PCC suggesting that the Paneth cell is the principal source of jejunal lysozyme.

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Year:  1979        PMID： 761838      PMCID： PMC1418968          DOI： 10.1136/gut.20.1.55

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  13 in total

1.  METHOD FOR ASSAY OF INTESTINAL DISACCHARIDASES.

Authors:  A DAHLQVIST
Journal:  Anal Biochem       Date:  1964-01       Impact factor: 3.365

2.  Serum lysozyme in inflammatory bowel and coeliac disease.

Authors:  E Mallas; J M Terry; P Asquith; W T Cooke
Journal:  J Clin Pathol       Date:  1976-07       Impact factor: 3.411

3.  Effects of lysozyme on normal and transformed mammalian cells.

Authors:  E F Osserman; M Klockars; J Halper; R E Fischel
Journal:  Nature       Date:  1973-06-08       Impact factor: 49.962

4.  Paneth-cell function.

Authors:  B Creamer
Journal:  Lancet       Date:  1967-02-11       Impact factor: 79.321

5.  Paneth-cell deficiency.

Authors:  B Creamer; I J Pink
Journal:  Lancet       Date:  1967-02-11       Impact factor: 79.321

6.  Ultrastructural immunocytochemical localization of lysozyme in the Paneth cells of man.

Authors:  S L Erlandsen; J A Parsons; T D Taylor
Journal:  J Histochem Cytochem       Date:  1974-06       Impact factor: 2.479

7.  Investigation of possible intestinal peptidase deficiency in coeliac disease.

Authors:  H J Cornell; R R Townley
Journal:  Clin Chim Acta       Date:  1973-01-10       Impact factor: 3.786

8.  Paneth cell function: phagocytosis and intracellular digestion of intestinal microorganisms. I. Hexamita muris.

Authors:  S L Erlandsen; D G Chase
Journal:  J Ultrastruct Res       Date:  1972-11

Review 9.  Cytology of intestinal epithelial cells.

Authors:  P G Toner
Journal:  Int Rev Cytol       Date:  1968

10.  [Lysozyme as a local defense factor in the gastrointestinal tract of patients with chronic diseases of the digestive organs].

Authors:  T I Kudinova
Journal:  Antibiotiki       Date:  1976-05
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  4 in total

1.  Conspicuous enterocytic binding pattern for peanut lectin and malignant histiocytosis of the intestine.

Authors:  P Möller; B Schüle; U Römmele; M Hüpen
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1983

2.  Enumeration of Paneth cells in coeliac disease: comparison of conventional light microscopy and immunofluorescence staining for lysozyme.

Authors:  H Scott; P Brandtzaeg
Journal:  Gut       Date:  1981-10       Impact factor: 23.059

3.  A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

Authors:  Barbara Hrdlickova; Chris J Mulder; Georgia Malamut; Bertrand Meresse; Mathieu Platteel; Yoichiro Kamatani; Isis Ricaño-Ponce; Roy L J van Wanrooij; Maria M Zorro; Marc Jan Bonder; Javier Gutierrez-Achury; Christophe Cellier; Alexandra Zhernakova; Petula Nijeboer; Pilar Galan; Sebo Withoff; Mark Lathrop; Gerd Bouma; Ramnik J Xavier; Bana Jabri; Nadine C Bensussan; Cisca Wijmenga; Vinod Kumar
Journal:  Eur J Gastroenterol Hepatol       Date:  2018-08       Impact factor: 2.566

4.  Lysozyme in chronic liver disease: a biochemical and histological study.

Authors:  I H Manifold; F M Bishop; P Cloke; D R Triger; J C Underwood
Journal:  J Clin Pathol       Date:  1982-08       Impact factor: 3.411
  4 in total

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