Literature DB >> 7617524

The description of the gastrointestinal transit of pellets assessed by gamma scintigraphy using statistical moments.

F Podczeck1, J M Newton, K H Yuen.   

Abstract

The gastrointestinal transit of multiple units (e.g., pellets), as determined by gamma scintigraphy, has been characterized by the application of statistical moments. Stomach emptying profiles can be described comprehensively by Mean Gastric Residence Time (MGRT) and Variance of Gastric Residence Time (VGRT) and caecum arrival data by Mean Caecum Arrival Time (MCAT) and Variance of Caecal Arrival Time (VCAT). This maximizes the data available, which is not the case when only described as 50% values. The statistical moments provide different information about the data observed compared to the classical descriptors, as there was only limited correlation between these two sets of parameters. Statistical moments therefore provide an important quantification of the process studied, and they can be used in any statistical test, where it is required to compare different experimental conditions.

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Year:  1995        PMID: 7617524     DOI: 10.1023/a:1016200501563

Source DB:  PubMed          Journal:  Pharm Res        ISSN: 0724-8741            Impact factor:   4.200


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Journal:  Pharm Res       Date:  2002-09       Impact factor: 4.200

5.  Influence of post-transplant immunosuppressive therapy on gastrointestinal transit using biomagnetic method: a pilot study.

Authors:  Maria do Carmo B Teixeira; Madileine F Américo; Ricardo B Oliveira; José Ricardo A Miranda; Fernando G Romeiro; Luciana A Corá
Journal:  Dig Dis Sci       Date:  2014-08-22       Impact factor: 3.199

6.  The effect of polyethylene glycol 400 on gastrointestinal transit: implications for the formulation of poorly-water soluble drugs.

Authors:  A W Basit; J M Newton; M D Short; W A Waddington; P J Ell; L F Lacey
Journal:  Pharm Res       Date:  2001-08       Impact factor: 4.200

7.  Concentration-dependent effects of polyethylene glycol 400 on gastrointestinal transit and drug absorption.

Authors:  Julia D R Schulze; Wendy A Waddington; Peter J Eli; Gary E Parsons; Mark D Coffin; Abdul W Basit
Journal:  Pharm Res       Date:  2003-12       Impact factor: 4.200

8.  Gastric emptying of pellets under fasting conditions: a mathematical model.

Authors:  Igor Locatelli; Ales Mrhar; Marija Bogataj
Journal:  Pharm Res       Date:  2009-04-01       Impact factor: 4.200

9.  Mild diabetes: long-term effects on gastric motility evaluated in rats.

Authors:  Andrieli T Hauschildt; Luciana A Corá; Gustavo T Volpato; Yuri K Sinzato; Débora C Damasceno; Madileine F Américo
Journal:  Int J Exp Pathol       Date:  2018-02-26       Impact factor: 1.925

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Authors:  Caio C Quini; Madileine F Américo; Luciana A Corá; Marcos Ff Calabresi; Matheus Alvarez; Ricardo B Oliveira; Jose Ricardo A Miranda
Journal:  J Biol Eng       Date:  2012-05-15       Impact factor: 4.355

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