Literature DB >> 7617150

Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4.

T J Bushell1, D E Jane, H W Tse, J C Watkins, C H Davies, J Garthwaite, G L Collingridge.   

Abstract

A new mGluR antagonist, MAP4 (the alpha-methyl derivative of L-AP4), was found to antagonize the synaptic depressant actions of L-AP4 at the lateral perforant path synapse, in rat hippocampal slices.

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Year:  1995        PMID: 7617150     DOI: 10.1016/0028-3908(95)00012-u

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN: 0028-3908            Impact factor:   5.250


  7 in total

1.  Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.

Authors:  R Pekhletski; R Gerlai; L S Overstreet; X P Huang; N Agopyan; N T Slater; W Abramow-Newerly; J C Roder; D R Hampson
Journal:  J Neurosci       Date:  1996-10-15       Impact factor: 6.167

2.  Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7.

Authors:  G Sansig; T J Bushell; V R Clarke; A Rozov; N Burnashev; C Portet; F Gasparini; M Schmutz; K Klebs; R Shigemoto; P J Flor; R Kuhn; T Knoepfel; M Schroeder; D R Hampson; V J Collett; C Zhang; R M Duvoisin; G L Collingridge; H van Der Putten
Journal:  J Neurosci       Date:  2001-11-15       Impact factor: 6.167

3.  Epileptogenesis in vivo enhances the sensitivity of inhibitory presynaptic metabotropic glutamate receptors in basolateral amygdala neurons in vitro.

Authors:  V Neugebauer; N B Keele; P Shinnick-Gallagher
Journal:  J Neurosci       Date:  1997-02-01       Impact factor: 6.167

4.  Distinct subtypes of metabotropic glutamate receptors mediate differential actions on excitability of spinal respiratory motoneurons.

Authors:  X W Dong; J L Feldman
Journal:  J Neurosci       Date:  1999-07-01       Impact factor: 6.167

5.  Impaired D-serine-mediated cotransmission mediates cognitive dysfunction in epilepsy.

Authors:  Katharina Klatte; Timo Kirschstein; David Otte; Leonie Pothmann; Lorenz Müller; Tursonjan Tokay; Maria Kober; Mischa Uebachs; Andreas Zimmer; Heinz Beck
Journal:  J Neurosci       Date:  2013-08-07       Impact factor: 6.167

6.  Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.

Authors:  N Sekiyama; Y Hayashi; S Nakanishi; D E Jane; H W Tse; E F Birse; J C Watkins
Journal:  Br J Pharmacol       Date:  1996-04       Impact factor: 8.739

7.  Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices.

Authors:  T J Bushell; D E Jane; H W Tse; J C Watkins; J Garthwaite; G L Collingridge
Journal:  Br J Pharmacol       Date:  1996-04       Impact factor: 8.739

  7 in total

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