Literature DB >> 7616875

Influence of route of administration on progesterone metabolism.

B de Lignieres1, L Dennerstein, T Backstrom.   

Abstract

While inducing similar progesterone levels, the ratio of 5 alpha- and 5 beta-pregnanolone/progesterone plasma concentrations has been dramatically increased after oral as opposed to vaginal administration, in a cross-over study. The known psychotropic effects of 5 alpha- and 5 beta-pregnanolone lead to different indications and precautions for oral and vaginal administration of progesterone.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7616875     DOI： 10.1016/0378-5122(94)00882-8

Source DB:  PubMed          Journal:  Maturitas        ISSN： 0378-5122            Impact factor:   4.342


  13 in total

1.  Efficacy of progesterone and progestogens in management of premenstrual syndrome: systematic review.

Authors:  K Wyatt; P Dimmock; P Jones; M Obhrai; S O'Brien
Journal:  BMJ       Date:  2001-10-06

2.  Vaginal progesterone for prevention of preterm birth in asymptomatic high-risk women with a normal cervical length: a systematic review and meta-analysis protocol.

Authors:  Kimberley P Williams; Liam McAuliffe; Rosanna Diacci; Anne-Marie Aubin; Ashad Issah; Carol Wang; Jason Phung; Craig E Pennell
Journal:  Syst Rev       Date:  2021-05-21

3.  Allopregnanolone concentration and mood--a bimodal association in postmenopausal women treated with oral progesterone.

Authors:  Lotta Andréen; Inger Sundström-Poromaa; Marie Bixo; Sigrid Nyberg; Torbjörn Bäckström
Journal:  Psychopharmacology (Berl)       Date:  2006-05-25       Impact factor: 4.530

4.  Pharmacokinetic and behavioral effects of allopregnanolone in healthy women.

Authors:  Erika Timby; Matts Balgård; Sigrid Nyberg; Olav Spigset; Agneta Andersson; Joanna Porankiewicz-Asplund; Robert H Purdy; Di Zhu; Torbjörn Bäckström; Inger Sundström Poromaa
Journal:  Psychopharmacology (Berl)       Date:  2005-09-21       Impact factor: 4.530

Review 5.  The role of hormones and hormonal treatments in premenstrual syndrome.

Authors:  Torbjörn Bäckström; Lotta Andreen; Vita Birzniece; Inger Björn; Inga-Maj Johansson; Maud Nordenstam-Haghjo; Sigrid Nyberg; Inger Sundström-Poromaa; Göran Wahlström; Mingde Wang; Di Zhu
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749

6.  A screening study of drug-drug interactions in cerivastatin users: an adverse effect of clopidogrel.

Authors:  J S Floyd; R Kaspera; K D Marciante; N S Weiss; S R Heckbert; T Lumley; K L Wiggins; B Tamraz; P-Y Kwok; R A Totah; B M Psaty
Journal:  Clin Pharmacol Ther       Date:  2012-03-14       Impact factor: 6.875

7.  Progesterone in Peri- and Postmenopause: A Review.

Authors:  P-A Regidor
Journal:  Geburtshilfe Frauenheilkd       Date:  2014-11       Impact factor: 2.915

Review 8.  Vaginal rings for menopausal symptom relief.

Authors:  Susan A Ballagh
Journal:  Drugs Aging       Date:  2004       Impact factor: 3.923

9.  Pharmacokinetic Properties of Three Forms of Vaginal Progesterone Administered in Either Single Or Multiple Dose Regimen in Healthy Post-menopausal Chinese Women.

Authors:  Guolan Wu; Junchun Chen; Xingjiang Hu; Huili Zhou; Jian Liu; Duo Lv; Lihua Wu; Jianzhong Shentu
Journal:  Front Pharmacol       Date:  2017-04-20       Impact factor: 5.810

10.  Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure.

Authors:  Fernando M Reis; Larissa M Coutinho; Silvia Vannuccini; Frédéric Batteux; Charles Chapron; Felice Petraglia
Journal:  Hum Reprod Update       Date:  2020-06-18       Impact factor: 15.610
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.