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Literature DB >> 7613092

TFIIH: a link between transcription, DNA repair and cell cycle regulation.

T Seroz¹, J R Hwang, V Moncollin, J M Egly.

Abstract

TFIIH is a basal transcription factor for protein-coding genes. It contains ERCC2, ERCC3, MO15 and cyclin H, polypeptides implicated in nucleotide excision repair or cell cycle regulation. The dysfunction of TFIIH could result in a large panel of genetic disorders, such as xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy. This link between transcription, DNA repair and cell cycle has highlighted a complex and essential role for TFIIH in the cell and has provided much information on the molecular mechanisms of each of these cellular processes.

Entities: Disease Gene

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Year: 1995 PMID： 7613092 DOI： 10.1016/0959-437x(95)80011-5

Source DB: PubMed Journal: Curr Opin Genet Dev ISSN： 0959-437X Impact factor: 5.578

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Cited

20 in total

1. Discrete promoter elements affect specific properties of RNA polymerase II transcription complexes.

Authors: J W Steinke; S J Kopytek; D O Peterson
Journal: Nucleic Acids Res Date: 2000-07-15 Impact factor: 16.971

2. Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme.

Authors: X Shi; M Chang; A J Wolf; C H Chang; A A Frazer-Abel; P A Wade; Z F Burton; J A Jaehning
Journal: Mol Cell Biol Date: 1997-03 Impact factor: 4.272

3. Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.

Authors: Z Li; A Yu; A M Weiner
Journal: J Virol Date: 1998-05 Impact factor: 5.103

Review 4. p53-mediated protective responses to UV irradiation.

Authors: M L Smith; A J Fornace
Journal: Proc Natl Acad Sci U S A Date: 1997-11-11 Impact factor: 11.205

5. Heat-shock inactivation of the TFIIH-associated kinase and change in the phosphorylation sites on the C-terminal domain of RNA polymerase II.

Authors: M F Dubois; M Vincent; M Vigneron; J Adamczewski; J M Egly; O Bensaude
Journal: Nucleic Acids Res Date: 1997-02-15 Impact factor: 16.971

10. TATA-binding protein-like protein (TLP/TRF2/TLF) negatively regulates cell cycle progression and is required for the stress-mediated G(2) checkpoint.

Authors: Miho Shimada; Tomoyoshi Nakadai; Taka-Aki Tamura
Journal: Mol Cell Biol Date: 2003-06 Impact factor: 4.272

TFIIH: a link between transcription, DNA repair and cell cycle regulation.

1. Discrete promoter elements affect specific properties of RNA polymerase II transcription complexes.

2. Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme.

3. Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.

Review 4. p53-mediated protective responses to UV irradiation.

5. Heat-shock inactivation of the TFIIH-associated kinase and change in the phosphorylation sites on the C-terminal domain of RNA polymerase II.

6. Drosophila TFIIE: purification, cloning, and functional reconstitution.

7. A distinct cyclin-dependent kinase-activating kinase of Arabidopsis thaliana.

8. Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator.

9. p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.

10. TATA-binding protein-like protein (TLP/TRF2/TLF) negatively regulates cell cycle progression and is required for the stress-mediated G(2) checkpoint.