| Literature DB >> 7612273 |
J Yuan1.
Abstract
Recent evidence has shown that two of the three key genes in the programmed cell death pathway of Caenorhabditis elegans, ced-9 (a cell death suppressor) and ced-3 (a cell death inducer), encode proteins that share structural and functional similarities with the mammalian proto-oncogene product Bcl-2 and interleukin-1 beta converting enzyme, respectively. These findings reveal key molecules that control life and death decisions in vertebrates.Entities:
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Year: 1995 PMID: 7612273 DOI: 10.1016/0955-0674(95)80030-1
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382