Literature DB >> 7612272

Lysophosphatidic acid signalling.

W H Moolenaar1.   

Abstract

Lysophosphatidic acid is an intercellular phospholipid messenger that is released from platelets (and probably other cells) and evokes multiple biological responses, ranging from induction of mitogenesis to neurite retraction, by activating a specific G protein coupled receptor. Recent studies indicate that the lysophosphatidic acid receptor acts via the small GTP-binding proteins Ras and Rho to stimulate cell proliferation and to trigger actin-based cytoskeletal events, respectively.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7612272     DOI： 10.1016/0955-0674(95)80029-8

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  48 in total

1.  Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation.

Authors:  F J Thomson; T J Jess; C Moyes; R Plevin; G W Gould
Journal:  Biochem J       Date:  1997-08-01       Impact factor: 3.857

2.  Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation.

Authors:  Thomas P Kole; Yiider Tseng; Lawrence Huang; Joseph L Katz; Denis Wirtz
Journal:  Mol Biol Cell       Date:  2004-05-14       Impact factor: 4.138

Review 3.  Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.

Authors:  Victoria A Blaho; Timothy Hla
Journal:  Chem Rev       Date:  2011-09-22       Impact factor: 60.622

4.  The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents.

Authors:  D Wilhelm; K Bender; A Knebel; P Angel
Journal:  Mol Cell Biol       Date:  1997-08       Impact factor: 4.272

5.  An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases.

Authors:  A F Neuwald
Journal:  Protein Sci       Date:  1997-08       Impact factor: 6.725

6.  The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin.

Authors:  M A Wilk-Blaszczak; W D Singer; T Quill; B Miller; J A Frost; P C Sternweis; F Belardetti
Journal:  J Neurosci       Date:  1997-06-01       Impact factor: 6.167

7.  Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation.

Authors:  Martine Bot; Ilze Bot; Rubén Lopez-Vales; Chris H A van de Lest; Jean Sébastien Saulnier-Blache; J Bernd Helms; Samuel David; Theo J C van Berkel; Erik A L Biessen
Journal:  Am J Pathol       Date:  2010-04-29       Impact factor: 4.307

8.  Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway.

Authors:  J S Koh; W Lieberthal; S Heydrick; J S Levine
Journal:  J Clin Invest       Date:  1998-08-15       Impact factor: 14.808

9.  Macroscopic consequences of the action of phospholipase C on giant unilamellar liposomes.

Authors:  Juha M Holopainen; Miglena I Angelova; Tim Söderlund; Paavo K J Kinnunen
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

Review 10.  Epithelial restitution and wound healing in inflammatory bowel disease.

Authors:  Andreas Sturm; Axel U Dignass
Journal:  World J Gastroenterol       Date:  2008-01-21       Impact factor: 5.742
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.