Literature DB >> 7612003

Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases.

K Lockwood1, S Moesgaard, T Yamamoto, K Folkers.   

Abstract

Over 35 years, data and knowledge have internationally evolved from biochemical, biomedical and clinical research on vitamin Q10 (coenzyme Q10; CoQ10) and cancer, which led in 1993 to overt complete regression of the tumors in two cases of breast cancer. Continuing this research, three additional breast cancer patients also underwent a conventional protocol of therapy which included a daily oral dosage of 390 mg of vitamin Q10 (Bio-Quinone of Pharma Nord) during the complete trials over 3-5 years. The numerous metastases in the liver of a 44-year-old patient "disappeared," and no signs of metastases were found elsewhere. A 49-year-old patient, on a dosage of 390 mg of vitamin Q10, revealed no signs of tumor in the pleural cavity after six months, and her condition was excellent. A 75-year-old patient with carcinoma in one breast, after lumpectomy and 390 mg of CoQ10, showed no cancer in the tumor bed or metastases. Control blood levels of CoQ10 of 0.83-0.97 and of 0.62 micrograms/ml increased to 3.34-3.64 and to 3.77 micrograms/ml, respectively, on therapy with CoQ10 for patients A-MRH and EEL.

Entities:  

Mesh:

Substances:

Year:  1995        PMID: 7612003     DOI: 10.1006/bbrc.1995.1952

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  9 in total

1.  AGO Recommendations for Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer. Update 2011.

Authors:  Christoph Thomssen; Anton Scharl; Nadia Harbeck
Journal:  Breast Care (Basel)       Date:  2011-08-30       Impact factor: 2.860

2.  Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer.

Authors:  Selvanathan Saravana Perumal; Palanivelu Shanthi; Panchanadham Sachdanandam
Journal:  Mol Cell Biochem       Date:  2005-05       Impact factor: 3.396

3.  Low plasma coenzyme Q(10) levels and breast cancer risk in Chinese women.

Authors:  Robert V Cooney; Qi Dai; Yu-Tang Gao; Wong-Ho Chow; Adrian A Franke; Xiao-Ou Shu; Honglan Li; Butian Ji; Qiuyin Cai; Weiwen Chai; Wei Zheng
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-04-05       Impact factor: 4.254

4.  Coenzyme Q10: is there a clinical role and a case for measurement?

Authors:  Sarah L Molyneux; Joanna M Young; Christopher M Florkowski; Michael Lever; Peter M George
Journal:  Clin Biochem Rev       Date:  2008-05

5.  Effects of coenzyme Q10 supplementation on inflammation, angiogenesis, and oxidative stress in breast cancer patients: a systematic review and meta-analysis of randomized controlled- trials.

Authors:  Mina Alimohammadi; Ali Rahimi; Fatemeh Faramarzi; Monireh Golpour; Reza Jafari-Shakib; Reza Alizadeh-Navaei; Alireza Rafiei
Journal:  Inflammopharmacology       Date:  2021-05-18       Impact factor: 4.473

6.  Enrichment of coenzyme Q10 in plasma and blood cells: defense against oxidative damage.

Authors:  Petra Niklowitz; Anka Sonnenschein; Bernd Janetzky; Werner Andler; Thomas Menke
Journal:  Int J Biol Sci       Date:  2007-04-05       Impact factor: 6.580

7.  Coenzyme q10 liquid supplementation in dyslipidemic subjects with statin-related clinical symptoms: a double-blind, randomized, placebo-controlled study.

Authors:  Giuseppe Derosa; Angela D'Angelo; Pamela Maffioli
Journal:  Drug Des Devel Ther       Date:  2019-10-21       Impact factor: 4.162

8.  Health food store recommendations: implications for breast cancer patients.

Authors:  Edward Mills; Edzard Ernst; Rana Singh; Cory Ross; Kumanan Wilson
Journal:  Breast Cancer Res       Date:  2003-08-06       Impact factor: 6.466

9.  Clinical Response of Metastatic Breast Cancer to Multi-targeted Therapeutic Approach: A Single Case Report.

Authors:  Christian Meiners
Journal:  Cancers (Basel)       Date:  2011-03-17       Impact factor: 6.639

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.