Literature DB >> 7609907

Activation of dopamine D1 receptors enhances long-term depression of synaptic transmission induced by low frequency stimulation in rat hippocampal CA1 neurons.

Z Chen1, S Fujii, K Ito, H Kato, K Kaneko, H Miyakawa.   

Abstract

The effects of both activation and blockade of dopamine (DA) D1 receptors on long-term depression (LTD) of synaptic transmission were examined in CA1 neurons of rat hippocampal slices. Low frequency stimulation (LFS) consisting of 450 pulses at 1 Hz induced LTD (-14.3%, mean, n = 10) in the slope of the field excitatory postsynaptic potential. SKF-38393 (3-10 microM), an agonist of DA D1 receptors, significantly enhanced LFS-induced LTD (-31.1%, n = 11). SCH-23390 (2 microM), an antagonist of DA D1 receptors, blocked the induction of LTD by LFS (2.5%, n = 6). These results indicate that DA D1 receptors play an important role in the modulation of LFS-induced LTD in rat hippocampal CA1 neurons.

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Year:  1995        PMID： 7609907     DOI： 10.1016/0304-3940(95)11430-5

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  7 in total

1.  Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses.

Authors:  Ji-Chuan Zhang; Pak-Ming Lau; Guo-Qiang Bi
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-20       Impact factor: 11.205

2.  Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors.

Authors:  P Calabresi; A Saiardi; A Pisani; J H Baik; D Centonze; N B Mercuri; G Bernardi; E Borrelli
Journal:  J Neurosci       Date:  1997-06-15       Impact factor: 6.167

3.  Behavioral and neurochemical recovery from partial 6-hydroxydopamine lesions of the substantia nigra is blocked by daily treatment with D1/D5, but not D2, dopamine receptor antagonists.

Authors:  A Emmi; H Rajabi; J Stewart
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

4.  D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses.

Authors:  N A Otmakhova; J E Lisman
Journal:  J Neurosci       Date:  1996-12-01       Impact factor: 6.167

5.  A computational model of dopaminergic modulation of hippocampal Schaffer collateral-CA1 long-term plasticity.

Authors:  Joseph T Schmalz; Gautam Kumar
Journal:  J Comput Neurosci       Date:  2021-08-25       Impact factor: 1.621

6.  Acute ketamine induces hippocampal synaptic depression and spatial memory impairment through dopamine D1/D5 receptors.

Authors:  Ting-Ting Duan; Ji-Wei Tan; Qiang Yuan; Jun Cao; Qi-Xin Zhou; Lin Xu
Journal:  Psychopharmacology (Berl)       Date:  2013-03-14       Impact factor: 4.530

Review 7.  Dopamine D1/D5 receptors mediate informational saliency that promotes persistent hippocampal long-term plasticity.

Authors:  Niels Hansen; Denise Manahan-Vaughan
Journal:  Cereb Cortex       Date:  2012-11-25       Impact factor: 5.357
  7 in total

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