| Literature DB >> 7607567 |
E V Murphy1, Y Zhang, W Zhu, J Biggs.
Abstract
We report the cloning of a cDNA encoding GliPR (glioma pathogenesis-related protein), a protein that is structurally similar to plant pathogenesis-related proteins. The GLIPR gene is highly expressed in the human brain tumor, glioblastoma multiforme/astrocytoma, but neither in normal fetal or adult brain tissue, nor in other nervous system tumors. GliPR shares up to 50% amino acid (aa) homology with plant pathogenesis-related proteins, group 1, over a region that comprises almost two thirds of the protein. We speculate that there may be functional similarities between the human and plant proteins as well.Entities:
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Year: 1995 PMID： 7607567 DOI： 10.1016/0378-1119(95)00061-a
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688