Literature DB >> 7606938

Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients.

M S Bianchi1, N O Bianchi, G Bailliet.   

Abstract

We have characterized the mtDNA in normal and breast cancer tissues from seven patients. Both types of tissue showed point mutation heteroplasmies and extensive deletions of the mtDNA. The analysis of these polymorphisms allowed us to infer the mtDNA composition of the breast cell that underwent malignant transformation.

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Year:  1995        PMID： 7606938     DOI： 10.1159/000134072

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  26 in total

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