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Literature DB >> 7605340

On the importance of the "antagonist assumption" to how receptors express themselves.

T Kenakin¹, P Morgan, M Lutz.

Abstract

Mesh：

Substances：
Receptors, Drug

Year: 1995 PMID： 7605340 DOI： 10.1016/0006-2952(95)00137-o

Source DB: PubMed Journal: Biochem Pharmacol ISSN： 0006-2952 Impact factor: 5.858

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7 in total

1. Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout.

Authors: I Muramatsu; S Morishima; F Suzuki; H Yoshiki; A S M Anisuzzaman; T Tanaka; M C Rodrigo; B E Myagmar; P C Simpson
Journal: Br J Pharmacol Date: 2008-09-22 Impact factor: 8.739

2. Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Authors: J Jakubík; L Bacáková; V Lisá; E E el-Fakahany; S Tucek
Journal: Proc Natl Acad Sci U S A Date: 1996-08-06 Impact factor: 11.205

3. Pharmacologically distinct phenotypes of α1B -adrenoceptors: variation in binding and functional affinities for antagonists.

Authors: Hatsumi Yoshiki; Junsuke Uwada; Abu Syed Md Anisuzzaman; Hidenori Umada; Ryoji Hayashi; Mie Kainoh; Takayoshi Masuoka; Matomo Nishio; Ikunobu Muramatsu
Journal: Br J Pharmacol Date: 2014-09-05 Impact factor: 8.739

On the importance of the "antagonist assumption" to how receptors express themselves.

1. Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout.

2. Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

3. Pharmacologically distinct phenotypes of α1B -adrenoceptors: variation in binding and functional affinities for antagonists.

Review 4. Phenotype pharmacology of lower urinary tract α(1)-adrenoceptors.

5. A study of antagonist affinities for the human histamine H2 receptor.

6. Native profiles of alpha(1A)-adrenoceptor phenotypes in rabbit prostate.

Review 7. Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates.