Literature DB >> 7604756

Possible evidence of angiotensin II and endogenous opioid modulation of novelty-induced rearing in the rat.

A A Ajayi1, O E Ukponmwan.   

Abstract

Rats treated with captopril (CAP, 10mg/kg i.p.) naltrexone (Nalx 0.1 mg/kg i.p) and saralasine (100 micrograms/kg i.p) displayed significantly less novelty-induced rearing (NIR) compared to saline injected animals. Naltrexone potentiated the inhibitory effect of CAP on NIR. Pretreatment with NALX did not alter SARA-induced decrease in NIR. It is suggested that the endogenous release of AII and/or opioids somehow modulate basal rearing activity.

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Year:  1994        PMID： 7604756

Source DB:  PubMed          Journal:  Afr J Med Med Sci        ISSN： 0309-3913


  10 in total

1.  Neuropharmacological effects of Nigerian honey in mice.

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Journal:  Afr J Tradit Complement Altern Med       Date:  2011-04-02

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Authors:  O J Onaolapo; T B Paul; A Y Onaolapo
Journal:  Metab Brain Dis       Date:  2017-05-15       Impact factor: 3.584

3.  Effect of fractionated extracts and isolated pure compounds of Spondias mombin (L. Anacardiaceae) leaves on novelty-induced rearing and grooming behaviours in mice.

Authors:  Abiodun O Ayoka; Rotimi A Owolabi; Samuel K Bamitale; Rufus O Akomolafe; Joseph A Aladesanmi; Eghe O Ukponmwan
Journal:  Afr J Tradit Complement Altern Med       Date:  2013-08-12

4.  Sedative and anxiolytic effects of the extracts of the leaves of Stachytarpheta cayennensis in mice.

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5.  Neuropharmacological profile of aqueous extract of Anaphe venata larva (Notondotidae) in rats.

Authors:  K D S Bamitale; M A Akanmu; Otas E Ukponmwan
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6.  Antipsychotic-like effect of minocycline in a rat model.

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7.  Subchronic Oral Bromocriptine Methanesulfonate Enhances Open Field Novelty-Induced Behavior and Spatial Memory in Male Swiss Albino Mice.

Authors:  Olakunle James Onaolapo; Adejoke Yetunde Onaolapo
Journal:  Neurosci J       Date:  2012-12-06

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Authors:  Oytun Erbaş; Hüseyin Serdar Akseki; Betül Eliküçük; Dilek Taşkıran
Journal:  ScientificWorldJournal       Date:  2013-10-22

9.  Foraging enrichment modulates open field response to monosodium glutamate in mice.

Authors:  Olakunle J Onaolapo; Adejoke Y Onaolapo; Moses A Akanmu; Gbola Olayiwola
Journal:  Ann Neurosci       Date:  2015-07

10.  Central depressant and nootropic effects of daytime melatonin in mice.

Authors:  Olakunle J Onaolapo; Adejoke Y Onaolapo; Akanni A Abiola; Eniafe A Lillian
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  10 in total

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