Literature DB >> 7601947

False-negative findings in skin cancer and melanoma screening.

F H Rampen1, J I Casparie-van Velsen, B E van Huystee, L A Kiemeney, L J Schouten.   

Abstract

BACKGROUND: Few data are available on the accuracy of visual skin examination by dermatologists as a skin cancer and melanoma screening tool.
OBJECTIVE: The purpose of this study was to assess the number of false-negative findings in a skin cancer-melanoma screening program.
METHODS: We obtained follow-up information regarding 1551 persons with a negative screening result in a skin cancer-melanoma screening program in 1990. Follow-up was established by record linkage with two different population-based registries.
RESULTS: Fifteen persons had new skin cancers. Three of their lesions had been present at the original screening and had probably been missed; 12 were genuinely new. No melanomas were among the missed cases. The calculated sensitivity of the screening was 93.3%, its specificity was 97.8%, its positive predictive value was 54.0%, and its negative predictive value was 99.8%.
CONCLUSION: Visual examination by dermatologists as a screening tool for skin cancer and melanoma is appropriate.

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Year:  1995        PMID: 7601947     DOI: 10.1016/0190-9622(95)90011-x

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  3 in total

Review 1.  Critical evaluation of diagnostic aids for the detection of oral cancer.

Authors:  Mark W Lingen; John R Kalmar; Theodore Karrison; Paul M Speight
Journal:  Oral Oncol       Date:  2007-09-06       Impact factor: 5.337

2.  Skin cancer discovery during total body skin examinations.

Authors:  Angela Jiang; Itisha S Jefferson; S Kayo Robinson; Dana Griffin; William Adams; Jodi Speiser; Laura Winterfield; Anthony Peterson; Eleanor Tung-Hahn; Kristin Lee; David Surprenant; Anne Coakley; Rebecca Tung; Murad Alam
Journal:  Int J Womens Dermatol       Date:  2021-05-30

3.  Systematic review of diagnostic accuracy of reflectance confocal microscopy for melanoma diagnosis in patients with clinically equivocal skin lesions.

Authors:  Alexander D Stevenson; Sharon Mickan; Susan Mallett; Mekhala Ayya
Journal:  Dermatol Pract Concept       Date:  2013-10-31
  3 in total

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