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Literature DB >> 7599274

Cap binding complexes and cellular growth control.

Abstract

The cap-binding complex eIF-4F plays a major role in the control of translation initiation, and overexpression of its limiting subunit, eIF-4E, leads to the deregulation of cellular growth. The recent cloning of eIF-4E binding proteins (4E-BPs) has uncovered a previously unsuspected pathway for the regulation of eIF-4E activity, through sequestration of eIF-4E as a complex with 4E-BPs.

Entities: Chemical Gene

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Year: 1995 PMID： 7599274 DOI： 10.1016/0300-9084(96)88102-8

Source DB: PubMed Journal: Biochimie ISSN： 0300-9084 Impact factor: 4.079

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Cited

11 in total

Review 1. Translational regulation in the chloroplast.

Authors: A Danon
Journal: Plant Physiol Date: 1997-12 Impact factor: 8.340

2. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression.

Authors: I Mothe-Satney; D Yang; P Fadden; T A Haystead; J C Lawrence
Journal: Mol Cell Biol Date: 2000-05 Impact factor: 4.272

3. A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E.

Authors: J Dostie; M Ferraiuolo; A Pause; S A Adam; N Sonenberg
Journal: EMBO J Date: 2000-06-15 Impact factor: 11.598

4. Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

Authors: V A Polunovsky; I B Rosenwald; A T Tan; J White; L Chiang; N Sonenberg; P B Bitterman
Journal: Mol Cell Biol Date: 1996-11 Impact factor: 4.272

9. Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation.

Authors: D Feigenblum; R J Schneider
Journal: Mol Cell Biol Date: 1996-10 Impact factor: 4.272

10. Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development.

Authors: Vincenzo Zappavigna; Federica Piccioni; J Carlos Villaescusa; Arturo C Verrotti
Journal: Proc Natl Acad Sci U S A Date: 2004-10-01 Impact factor: 11.205

Cap binding complexes and cellular growth control.

Review 1. Translational regulation in the chloroplast.

2. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression.

3. A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E.

4. Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

5. Expression of the translational repressor NAT1 in experimental models of cardiac hypertrophy.

6. Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP.

7. A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.

8. Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease.

9. Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation.

10. Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development.