OBJECTIVE: To characterize the otolaryngologic manifestations of amyloidosis; classify patients with amyloidosis by specific location and type of underlying disease; and compare disease presentation and long-term outcome in these patients. DESIGN: Retrospective review of biopsy specimens recorded as amyloidosis. SETTING: Tertiary care referral center serving a diverse patient base. PATIENTS: Of 141 patients with biopsy-verified amyloidosis who met the inclusion criterion for the study, 27 (19%) had head and neck manifestations. OUTCOME MEASURES: Good functional outcome and survival of patients with amyloidosis. RESULTS: The tongue was the most commonly affected site of the head and neck. Distinct differences exist in functional outcome and long-term survival in patients with the localized form of amyloidosis when compared with patients with systemic amyloidosis. CONCLUSION: Because amyloidosis often affects the head and neck, otolaryngologists need to be familiar with this disease.
OBJECTIVE: To characterize the otolaryngologic manifestations of amyloidosis; classify patients with amyloidosis by specific location and type of underlying disease; and compare disease presentation and long-term outcome in these patients. DESIGN: Retrospective review of biopsy specimens recorded as amyloidosis. SETTING: Tertiary care referral center serving a diverse patient base. PATIENTS: Of 141 patients with biopsy-verified amyloidosis who met the inclusion criterion for the study, 27 (19%) had head and neck manifestations. OUTCOME MEASURES: Good functional outcome and survival of patients with amyloidosis. RESULTS: The tongue was the most commonly affected site of the head and neck. Distinct differences exist in functional outcome and long-term survival in patients with the localized form of amyloidosis when compared with patients with systemic amyloidosis. CONCLUSION: Because amyloidosis often affects the head and neck, otolaryngologists need to be familiar with this disease.
Authors: Hélen Kaline Farias Bezerra; Talita Ribeiro Tenório de França; José Divaldo Prado; Rafael Segura Saint-Gerons; Elaine Judite de Amorim Carvalho; Danyel Elias da Cruz Perez Journal: Head Neck Pathol Date: 2022-03-16
Authors: Thorsten Send; Jennifer L Spiegel; Goetz Schade; Annette Pantelis; Arno Olthoff; Friedrich Bootz; Martin Canis; Mark Jakob Journal: Dysphagia Date: 2018-10-31 Impact factor: 3.438
Authors: Flávia Sayuri Matsuo; Luiz Fernando Barbosa de Paulo; João Paulo Silva Servato; Paulo Rogério de Faria; Sergio Vitorino Cardoso; Adriano Mota Loyola Journal: Clin Oral Investig Date: 2015-11-10 Impact factor: 3.573