Literature DB >> 7596928

Neurosarcoidosis masquerading as glioma of the optic chiasm in a child.

K L Ng1, N McDermott, C A Romanowski, A Jackson.   

Abstract

We present a case of sarcoidosis in a 14-year-old girl who presented with a short history of visual disturbance. Computed tomography and magnetic resonance imaging (MRI) demonstrated enlargement of the optic chiasm and prechiasmic optic nerves. Post-contrast MRI showed marginal enhancement of the affected areas of the optic pathways. A diagnosis of optic nerve glioma and arachnoid gliomatosis was made; surgical confirmation was not sought due to the risk to vision associated with biopsy. A rapid clinical deterioration led to repeat MRI which demonstrated extensive enhancing soft tissue throughout the basal cisterns with extension into the brain. Biopsy confirmed a diagnosis of sarcoidosis.

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Year:  1995        PMID: 7596928      PMCID: PMC2398118          DOI: 10.1136/pgmj.71.835.265

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  7 in total

Review 1.  Neurologic manifestations in sarcoidosis: review of the literature, with a report of 23 cases.

Authors:  P Delaney
Journal:  Ann Intern Med       Date:  1977-09       Impact factor: 25.391

2.  Childhood chiasmal gliomas: update on the fate of patients in the 1969 San Francisco Study.

Authors:  R K Imes; W F Hoyt
Journal:  Br J Ophthalmol       Date:  1986-03       Impact factor: 4.638

3.  Magnetic resonance imaging in central nervous system sarcoidosis.

Authors:  D H Miller; B E Kendall; S Barter; G Johnson; D G MacManus; S J Logsdail; I E Ormerod; W I McDonald
Journal:  Neurology       Date:  1988-03       Impact factor: 9.910

4.  Central nervous system sarcoidosis.

Authors:  B Pentland; J D Mitchell; R E Cull; M J Ford
Journal:  Q J Med       Date:  1985-08

5.  CNS sarcoidosis: evaluation with contrast-enhanced MR imaging.

Authors:  S Seltzer; A S Mark; S W Atlas
Journal:  AJNR Am J Neuroradiol       Date:  1991 Nov-Dec       Impact factor: 3.825

6.  Sarcoidosis of the central nervous system.

Authors:  A C Douglas; A F Maloney
Journal:  J Neurol Neurosurg Psychiatry       Date:  1973-12       Impact factor: 10.154

7.  MRI in neurosarcoidosis.

Authors:  A Zouaoui; J C Maillard; D Dormont; J Chiras; C Marsault
Journal:  J Neuroradiol       Date:  1992-12       Impact factor: 3.447

  7 in total
  1 in total

1.  Isolated optic nerve sarcoidosis.

Authors:  Sandip Suresh; Gregory S Kosmorsky; Michael S Lee
Journal:  Sarcoidosis Vasc Diffuse Lung Dis       Date:  2017-04-28       Impact factor: 0.670

  1 in total

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