| Literature DB >> 7593539 |
Abstract
A general model is put forward to explain the mechanism by which age-associated aneuploidies are produced. This is based on the free radical theory of ageing, which assumes a rise in oxidative stress with age. It is proposed that determination of indicators of oxidative stress in oocytes from various sources could be a first step in the testing of this hypothesis.Entities:
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Year: 1995 PMID: 7593539 DOI: 10.1093/humrep/10.6.1563
Source DB: PubMed Journal: Hum Reprod ISSN: 0268-1161 Impact factor: 6.918