Literature DB >> 7592066

Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101.

K Dornberger1, W Ihn, M Ritzau, U Gräfe, B Schlegel, W F Fleck, J W Metzger.   

Abstract

Four new members of peptaibol antibiotics, designated as chrysospermins A, B, C, and D, were isolated from the mycelium of Apiocrea chrysosperma Ap101 by solvent extraction, silica gel chromatography and preparative recycling HPLC. Their structures as new nonadecapeptides were settled by detailed spectroscopic analysis and chemical degradation experiments. The chrysospermins display antibacterial and antifungal activity, and induce pigment formation by the fungus Phoma destructiva.

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Year:  1995        PMID： 7592066     DOI： 10.7164/antibiotics.48.977

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  4 in total

1.  2D relayed anisotropy correlation NMR: characterization of the 13C' chemical shift tensor orientation in the peptide plane of the dipeptide AibAib.

Authors:  B Heise; J Leppert; H Wenschuh; O Ohlenschläger; M Görlach; R Ramachandran
Journal:  J Biomol NMR       Date:  2001-02       Impact factor: 2.835

2.  Structural elucidation of XR586, a peptaibol-like antibiotic from Acremonium persicinum.

Authors:  G J Sharman; A C Try; D H Williams; A M Ainsworth; R Beneyto; T M Gibson; C McNicholas; D V Renno; N Robinson; K A Wood; S K Wrigley
Journal:  Biochem J       Date:  1996-12-15       Impact factor: 3.857

3.  Rare Glutamic Acid Methyl Ester Peptaibols from Sepedonium ampullosporum Damon KSH 534 Exhibit Promising Antifungal and Anticancer Activity.

Authors:  Yen T H Lam; Manuel G Ricardo; Robert Rennert; Andrej Frolov; Andrea Porzel; Wolfgang Brandt; Pauline Stark; Bernhard Westermann; Norbert Arnold
Journal:  Int J Mol Sci       Date:  2021-11-24       Impact factor: 5.923

4.  Screening the biosphere: the fungicolous fungus Trichoderma phellinicola, a prolific source of hypophellins, new 17-, 18-, 19-, and 20-residue peptaibiotics.

Authors:  Christian René Röhrich; Anita Iversen; Walter Michael Jaklitsch; Hermann Voglmayr; Andreas Vilcinskas; Kristian Fog Nielsen; Ulf Thrane; Hans von Döhren; Hans Brückner; Thomas Degenkolb
Journal:  Chem Biodivers       Date:  2013-05       Impact factor: 2.408
  4 in total

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