Literature DB >> 759086

MIC-II - a program for the determination of cardiac output, arterio-venous shunt and regional blood flow using the radioactive microsphere method.

R Schosser, K E Arfors, K Messmer.   

Abstract

MIC-II is a versatile BASIC computer program designed to calculate the cardiac output, the arterio-venous shunt and the regional blood flow from data obtained by the radioactive microsphere method. The samples are measured in a gammaspectrometer with a multichannel pulse height analyzer and the data are recorded on tape. Up to 10 different nuclides may be used simultaneously, including tracers which are not bound to microspheres. The nuclides may have overlapping energy spectra. The analysis of the energy spectra is performed according to the matrix method. Standard samples, each containing one pure nuclide, are measured to obtained the overlap matrix. The unkown amounts of the nuclides in the samples are obtained by solving a system of simultaneous linear equations. Up to 100 organ samples may be taken in one experiment. Up to 10 different organ maps, containing a text label for each organ specimen, may be created, edited, modified and stored on tape for convenient identification of input and output. Numerous validity checks for imput and output make MIC-II easy to use, even for non-computer trained personel.

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Year:  1979        PMID: 759086     DOI: 10.1016/0010-468x(79)90014-x

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN: 0010-468X


  13 in total

1.  From piecewise to full physiologic pharmacokinetic modeling: applied to thiopental disposition in the rat.

Authors:  W F Ebling; D R Wada; D R Stanski
Journal:  J Pharmacokinet Biopharm       Date:  1994-08

Review 2.  Glossary: methods for the measurement of coronary blood flow and myocardial perfusion.

Authors:  S G Sakka; D R Wallbridge; G Heusch
Journal:  Basic Res Cardiol       Date:  1996 Mar-Apr       Impact factor: 17.165

3.  Cardiovascular effects of apamin and BRL 34915 in rats and rabbits.

Authors:  N S Cook; R P Hof
Journal:  Br J Pharmacol       Date:  1988-01       Impact factor: 8.739

4.  Regional changes in cerebral blood flow during acute endotoxemia.

Authors:  Z Yang; U Kreimeir; K Messmer
Journal:  J Tongji Med Univ       Date:  1987

5.  Blood flow distribution in the left ventricular free wall in open-chest dogs.

Authors:  F W Prinzen; G J van der Vusse; R S Reneman
Journal:  Basic Res Cardiol       Date:  1981 Jul-Aug       Impact factor: 17.165

6.  Myocardial characteristics of thyroxine stimulated hypertrophy. A structural and functional study.

Authors:  E A Breisch; F C White; H K Hammond; S Flynn; C M Bloor
Journal:  Basic Res Cardiol       Date:  1989 Jul-Aug       Impact factor: 17.165

7.  The influence of PEEP ventilation on organ blood flow and peripheral oxygen delivery.

Authors:  J Beyer; P Beckenlechner; K Messmer
Journal:  Intensive Care Med       Date:  1982-03       Impact factor: 17.440

8.  The effect of elevated arterial free fatty acid concentrations on hemodynamics and myocardial metabolism and blood flow during ischemia.

Authors:  F W Prinzen; G J van der Vusse; W A Coumans; R Kruger; C W Verlaan; R S Reneman
Journal:  Basic Res Cardiol       Date:  1981 Mar-Apr       Impact factor: 17.165

9.  Three-dimensional analysis of regional mechanical function, blood flow and electrophysiological parameters during early myocardial ischemia in dogs.

Authors:  P Kowallik; D Baumgart; A Skyschally; T Ehring; G Heusch
Journal:  Basic Res Cardiol       Date:  1992 May-Jun       Impact factor: 17.165

10.  Vasopressin induced myocardial depression in neurally mediated and not due to impaired coronary blood flow.

Authors:  R P Hof
Journal:  Br J Pharmacol       Date:  1986-03       Impact factor: 8.739

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