Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Coactosin interferes with the capping of actin filaments.

Literature DB >> 7589554

Coactosin interferes with the capping of actin filaments.

U Röhrig¹, G Gerisch, L Morozova, M Schleicher, A Wegner.

Abstract

Coactosin, a 16 kDa protein associated with the actin cytoskeleton from Dictyostelium discoideum, was purified by an improved method, in which other components of the cytoskeleton were removed. The highly purified coactosin had no effect on the time course of actin polymerization, but when added to actin in presence of capping proteins, coactosin counteracted the capping activity of these proteins. The capping proteins cap32/34 and severin domain 1 retarded actin polymerization, on addition of coactosin to samples containing one of these capping proteins the time course of actin polymerization became close to controls without capping proteins.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1995 PMID： 7589554 DOI： 10.1016/0014-5793(95)01130-7

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

Keyword Cloud
Cited

11 in total

1. (1)H, (13)C and (15)N resonance assignments of coactosin, a cytoskeletal regulatory protein.

Authors: Maarit Hellman; Ville Paavilainen; Arto Annila; Pekka Lappalainen; Perttu Permi
Journal: J Biomol NMR Date: 2004-11 Impact factor: 2.835

2. NMR structure of human coactosin-like protein.

Authors: Edvards Liepinsh; Marija Rakonjac; Vincent Boissonneault; Patrick Provost; Bengt Samuelsson; Olof Rådmark; Gottfried Otting
Journal: J Biomol NMR Date: 2004-11 Impact factor: 2.835

3. SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors.

Authors: O Larbolette; B Wollscheid; J Schweikert; P J Nielsen; J Wienands
Journal: Mol Cell Biol Date: 1999-02 Impact factor: 4.272

4. A genomewide overexpression screen identifies genes involved in the phosphatidylinositol 3-kinase pathway in the human protozoan parasite Entamoeba histolytica.

Authors: Amrita B Koushik; Brenda H Welter; Michelle L Rock; Lesly A Temesvari
Journal: Eukaryot Cell Date: 2014-01-17

Coactosin interferes with the capping of actin filaments.

1. (1)H, (13)C and (15)N resonance assignments of coactosin, a cytoskeletal regulatory protein.

2. NMR structure of human coactosin-like protein.

3. SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors.

4. A genomewide overexpression screen identifies genes involved in the phosphatidylinositol 3-kinase pathway in the human protozoan parasite Entamoeba histolytica.

5. Mammalian CARMIL inhibits actin filament capping by capping protein.

6. Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75.

7. Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum.

8. Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility.

9. 1H, 13C and 15N resonance assignments and the secondary structures of human coactosin like protein (hCLP) D123N.

10. Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse.