Literature DB >> 7587111

Acute myeloid leukemia with Inv (16) produces a chimeric transcription factor with a myosin heavy chain tail.

P Liu1, N Seidel, D Bodine, N Speck, S Tarlé, F S Collins.   

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Year:  1994        PMID: 7587111     DOI: 10.1101/sqb.1994.059.01.061

Source DB:  PubMed          Journal:  Cold Spring Harb Symp Quant Biol        ISSN: 0091-7451


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  6 in total

1.  Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein.

Authors:  Tanawan Kummalue; Jianrong Lou; Alan D Friedman
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

2.  Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Authors:  Q Wang; T Stacy; M Binder; M Marin-Padilla; A H Sharpe; N A Speck
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

3.  The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates.

Authors:  N Adya; T Stacy; N A Speck; P P Liu
Journal:  Mol Cell Biol       Date:  1998-12       Impact factor: 4.272

4.  The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia.

Authors:  S C Kogan; E Lagasse; S Atwater; S C Bae; I Weissman; Y Ito; J M Bishop
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205

5.  IL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival.

Authors:  Yiqian Wang; Lisa Richter; Michelle Becker; Catalina Amador; R Katherine Hyde
Journal:  Sci Rep       Date:  2019-02-11       Impact factor: 4.379

Review 6.  Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.

Authors:  Lisa Richter; Yiqian Wang; R Katherine Hyde
Journal:  Oncotarget       Date:  2016-10-04
  6 in total

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