Literature DB >> 7585630

The oncogene qin codes for a transcriptional repressor.

J Li1, H W Chang, E Lai, E J Parker, P K Vogt.   

Abstract

The retroviral oncogene qin codes for a protein that belongs to the winged helix family of transcriptional regulators. The Qin protein is localized in the nucleus and binds to the same DNA consensus sequence as rat brain factor 1 (BF-1). Cellular Qin shows greater affinity to DNA than does viral Qin. Alone or fused to the DNA-binding domain of the yeast GAL4 protein, both Qin proteins act as transcriptional repressors. The major transcriptional repression domain maps to the region of amino acids 252-395 of viral Qin.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7585630

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  17 in total

1.  BF-1 interferes with transforming growth factor beta signaling by associating with Smad partners.

Authors:  C Dou; J Lee; B Liu; F Liu; J Massague; S Xuan; E Lai
Journal:  Mol Cell Biol       Date:  2000-09       Impact factor: 4.272

2.  Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins.

Authors:  Masahiro Aoki; Hao Jiang; Peter K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-01       Impact factor: 11.205

3.  Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.

Authors:  Somasish Ghosh Dastidar; Sriram Narayanan; Stefano Stifani; Santosh R D'Mello
Journal:  J Biol Chem       Date:  2012-02-21       Impact factor: 5.157

Review 4.  In control of biology: of mice, men and Foxes.

Authors:  Patrick J E C Wijchers; J Peter H Burbach; Marten P Smidt
Journal:  Biochem J       Date:  2006-07-15       Impact factor: 3.857

5.  FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation.

Authors:  Martin Roth; Boyan Bonev; Jennefer Lindsay; Robert Lea; Niki Panagiotaki; Corinne Houart; Nancy Papalopulu
Journal:  Development       Date:  2010-03-31       Impact factor: 6.868

6.  FoxG1 promotes the survival of postmitotic neurons.

Authors:  Somasish Ghosh Dastidar; Paul Michael Zagala Landrieu; Santosh R D'Mello
Journal:  J Neurosci       Date:  2011-01-12       Impact factor: 6.167

7.  The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription.

Authors:  J Yao; E Lai; S Stifani
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

8.  Oncogenic transformation induced by the Qin protein is correlated with transcriptional repression.

Authors:  J Li; H Thurm; H W Chang; J S Iacovoni; P K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

9.  Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase.

Authors:  H Ye; A X Holterman; K W Yoo; R R Franks; R H Costa
Journal:  Mol Cell Biol       Date:  1999-12       Impact factor: 4.272

10.  Forkhead box O-class 1 and forkhead box G1 as prognostic markers for bladder cancer.

Authors:  Tae-Hwan Kim; Sung-Whan Jo; Young Suk Lee; Yong-June Kim; Sang-Cheol Lee; Wun-Jae Kim; Seok Joong Yun
Journal:  J Korean Med Sci       Date:  2009-06-12       Impact factor: 2.153
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.