Literature DB >> 7585607

Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer.

J A Macoska1, T M Trybus, P D Benson, W A Sakr, D J Grignon, K D Wojno, T Pietruk, I J Powell.   

Abstract

Allelic loss of human chromosome sequences is often equated with inactivation of putative tumor suppressor genes. Loss of sequences on the short arm of chromosome 8 (8p) has been observed in human cancers, especially of 8p22 in prostate tumors. By using PCR analysis of highly polymorphic microsatellite repeat markers at nine 8p loci in 135 tumors, we observed deletion of sequences at 8p22 and at two other proximal deletion domains. These novel deletion domains encompass the NEFL locus and D8S87-ANK1 loci, respectively. These data suggest that three 8p tumor suppressor gene loci may be independently deleted in human prostate cancers.

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Year:  1995        PMID： 7585607

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  35 in total

1.  High-resolution physical map and transcript identification of a prostate cancer deletion interval on 8p22.

Authors:  Z H Arbieva; K Banerjee; S Y Kim; S L Edassery; V S Maniatis; S K Horrigan; C A Westbrook
Journal:  Genome Res       Date:  2000-02       Impact factor: 9.043

2.  Linkage and association studies of prostate cancer susceptibility: evidence for linkage at 8p22-23.

Authors:  J Xu; S L Zheng; G A Hawkins; D A Faith; B Kelly; S D Isaacs; K E Wiley; B Chang ; C M Ewing; P Bujnovszky; J D Carpten; E R Bleecker; P C Walsh; J M Trent; D A Meyers; W B Isaacs
Journal:  Am J Hum Genet       Date:  2001-07-06       Impact factor: 11.025

3.  Fluorescence in situ hybridization evaluation of chromosome deletion patterns in prostate cancer.

Authors:  S F Huang; S Xiao; A A Renshaw; K R Loughlin; T J Hudson; J A Fletcher
Journal:  Am J Pathol       Date:  1996-11       Impact factor: 4.307

4.  Keynote address: prostate cancer among African-American men--from the bench to the community.

Authors:  I Powell
Journal:  J Natl Med Assoc       Date:  1998-11       Impact factor: 1.798

5.  Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25.

Authors:  R A McIndoe; J L Stanford; M Gibbs; G P Jarvik; S Brandzel; C L Neal; S Li; J T Gammack; A A Gay; E L Goode; L Hood; E A Ostrander
Journal:  Am J Hum Genet       Date:  1997-08       Impact factor: 11.025

6.  DLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity.

Authors:  Veenu Tripathi; Nicholas C Popescu; Drazen B Zimonjic
Journal:  Mol Cell Biol       Date:  2012-04-02       Impact factor: 4.272

7.  Frequent loss in chromosome 8p loci in liver cirrhosis accompanying hepatocellular carcinoma.

Authors:  Y Kishimoto; G Shiota; K Wada; M Kitano; K Nakamoto; Y Kamisaki; T Suou; T Itoh; H Kawasaki
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

8.  miRNA-429 Inhibits Astrocytoma Proliferation and Invasion by Targeting BMI1.

Authors:  Gang Peng; Yiwei Liao; Chenfu Shen
Journal:  Pathol Oncol Res       Date:  2016-09-23       Impact factor: 3.201

9.  Defining aggressive prostate cancer using a 12-gene model.

Authors:  Tarek A Bismar; Francesca Demichelis; Alberto Riva; Robert Kim; Sooryanarayana Varambally; Le He; Jeff Kutok; Jonathan C Aster; Jeffery Tang; Rainer Kuefer; Matthias D Hofer; Phillip G Febbo; Arul M Chinnaiyan; Mark A Rubin
Journal:  Neoplasia       Date:  2006-01       Impact factor: 5.715

10.  Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.

Authors:  H Song; B Zhang; M A Watson; P A Humphrey; H Lim; J Milbrandt
Journal:  Oncogene       Date:  2009-07-13       Impact factor: 9.867
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