Literature DB >> 7585207

DNA damage, p53 and anticancer therapies.

J Milner1.   

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Year:  1995        PMID: 7585207     DOI: 10.1038/nm0995-879

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


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  13 in total

1.  Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53.

Authors:  A L Okorokov; F Ponchel; J Milner
Journal:  EMBO J       Date:  1997-10-01       Impact factor: 11.598

2.  TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short-term radiotherapy in rectal cancer.

Authors:  Daniela Kandioler; Ronald Zwrtek; Carmen Ludwig; Elisabeth Janschek; Meinhard Ploner; Friedrich Hofbauer; Irene Kührer; Sonja Kappel; Friedrich Wrba; Manfred Horvath; Josef Karner; Karl Renner; Michael Bergmann; Judith Karner-Hanusch; Richard Pötter; Raimund Jakesz; Bela Teleky; Friedrich Herbst
Journal:  Ann Surg       Date:  2002-04       Impact factor: 12.969

3.  DNA mismatch repair enzyme hMSH2 in malignant melanoma: increased immunoreactivity as compared to acquired melanocytic nevi and strong mRNA expression in melanoma cell lines.

Authors:  K Rass; P Gutwein; C Welter; V Meineke; W Tilgen; J Reichrath
Journal:  Histochem J       Date:  2001-08

4.  Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations.

Authors:  R K Brachmann; K Yu; Y Eby; N P Pavletich; J D Boeke
Journal:  EMBO J       Date:  1998-04-01       Impact factor: 11.598

5.  Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells.

Authors:  Claudia Friesen; Annelie Lubatschofski; Jörg Kotzerke; Inga Buchmann; Sven N Reske; Klaus-Michael Debatin
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-06-26       Impact factor: 9.236

6.  Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability.

Authors:  P V Nikolova; J Henckel; D P Lane; A R Fersht
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

7.  Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.

Authors:  L M Leoni; Q Chao; H B Cottam; D Genini; M Rosenbach; C J Carrera; I Budihardjo; X Wang; D A Carson
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205

8.  Inhibition of cell growth, induction of apoptosis and mechanism of action of the novel platinum compound cis-diaminechloro-[2-(diethylamino) ethyl 4-amino-benzoate, N(4)]-chloride platinum (II) monohydrochloride monohydrate.

Authors:  Maria A Mariggiò; Sergio Cafaggi; Massimo Ottone; Brunella Parodi; Maria O Vannozzi; Vaclav Mandys; Maurizio Viale
Journal:  Invest New Drugs       Date:  2004-01       Impact factor: 3.850

9.  In vitro study on apoptosis induced by strontium-89 in human breast carcinoma cell line.

Authors:  Cheng Wang; Jing Wang; Han Jiang; Min Zhu; Baoguo Chen; Weiguang Bao
Journal:  J Biomed Biotechnol       Date:  2011-06-09

10.  p53 inactivation upregulates p73 expression through E2F-1 mediated transcription.

Authors:  Chaitali Tophkhane; Shi-He Yang; Yunbo Jiang; Zhikun Ma; Dharmalingam Subramaniam; Shrikant Anant; Shingo Yogosawa; Toshiyuki Sakai; Wan-Guo Liu; Susan Edgerton; Ann Thor; Xiaohe Yang
Journal:  PLoS One       Date:  2012-08-30       Impact factor: 3.240

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