Literature DB >> 75852

IgE-induced changes in human basophil cyclic AMP levels.

L M Lichtenstein, A K Sobotka, F J Malveaux, E Gillespie.   

Abstract

We studied a unique patient with 77% basophils, not different from normal by a number of criteria, in order to measure the changes in cyclic AMP level associated with IgE-mediated histamine release. In accordance with previous hypothesis and circumstantial evidence, anti-IgE challenge led to a significant fall in the cyclic AMP level which preceded histamine release.

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Year:  1978        PMID： 75852     DOI： 10.1159/000232059

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN： 0020-5915


  5 in total

1.  Adenosine inhibits and potentiates IgE-dependent histamine release from human basophils by an A2-receptor mediated mechanism.

Authors:  M K Church; S T Holgate; P J Hughes
Journal:  Br J Pharmacol       Date:  1983-12       Impact factor: 8.739

Review 2.  Basophils in human disease.

Authors:  E B Mitchell; P W Askenase
Journal:  Clin Rev Allergy       Date:  1983-09

3.  IgE receptors on human basophils. Relationship to serum IgE concentration.

Authors:  F J Malveaux; M C Conroy; N F Adkinson; L M Lichtenstein
Journal:  J Clin Invest       Date:  1978-07       Impact factor: 14.808

4.  Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction.

Authors:  N Frossard; Y Landry; G Pauli; M Ruckstuhl
Journal:  Br J Pharmacol       Date:  1981-08       Impact factor: 8.739

Review 5.  Effector cell heterogeneity in immediate hypersensitivity reactions.

Authors:  D D Metcalfe
Journal:  Clin Rev Allergy       Date:  1983-09
  5 in total

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