Literature DB >> 7583638

Cystine knots.

N W Isaacs1.   

Abstract

Recent reports of the crystal structure of the glycoprotein hormone human chorionic gonadotrophin show that cystine knots are proving to be versatile structural motifs that enable the construction of a variety of proteins with different functional properties. Because of their shape, there appears to be an intrinsic requirement for the cystine-knot growth factors to form dimers. This extra level of organization increases the variety of structures built around this simple structural motif.

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Year:  1995        PMID： 7583638     DOI： 10.1016/0959-440x(95)80102-2

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  39 in total

1.  Refocusing of B-cell responses following a single amino acid substitution in an antigen.

Authors:  M D Chiesa; P M Martensen; C Simmons; N Porakishvili; J Justesen; G Dougan; I M Roitt; P J Delves; T Lund
Journal:  Immunology       Date:  2001-06       Impact factor: 7.397

2.  Classification of protein disulphide-bridge topologies.

Authors:  J M Mas; P Aloy; M A Martí-Renom; B Oliva; R de Llorens; F X Avilés; E Querol
Journal:  J Comput Aided Mol Des       Date:  2001-05       Impact factor: 3.686

3.  Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose.

Authors:  R Kane; L Stevenson; C Godson; A W Stitt; C O'Brien
Journal:  Br J Ophthalmol       Date:  2005-12       Impact factor: 4.638

4.  Modeling the human intestinal mucin (MUC2) C-terminal cystine knot dimer.

Authors:  Vatsala D Sadasivan; Sandeep R Narpala; David E Budil; Albert Sacco; Rebecca L Carrier
Journal:  J Mol Model       Date:  2011-02-12       Impact factor: 1.810

5.  Characterization of the tomato Cf-4 gene for resistance to Cladosporium fulvum identifies sequences that determine recognitional specificity in Cf-4 and Cf-9.

Authors:  C M Thomas; D A Jones; M Parniske; K Harrison; P J Balint-Kurti; K Hatzixanthis; J D Jones
Journal:  Plant Cell       Date:  1997-12       Impact factor: 11.277

6.  Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.

Authors:  A Bergner; V Oganessyan; T Muta; S Iwanaga; D Typke; R Huber; W Bode
Journal:  EMBO J       Date:  1996-12-16       Impact factor: 11.598

7.  Chemical disulfide mapping identifies an inhibitor cystine knot in the agouti signaling protein.

Authors:  Bin Yu; Glenn L Millhauser
Journal:  FEBS Lett       Date:  2007-11-13       Impact factor: 4.124

8.  A High-Affinity Binding Site for the AVR9 Peptide Elicitor of Cladosporium fulvum Is Present on Plasma Membranes of Tomato and Other Solanaceous Plants.

Authors:  M. Kooman-Gersmann; G. Honee; G. Bonnema; PJGM. De Wit
Journal:  Plant Cell       Date:  1996-05       Impact factor: 11.277

9.  Correlation between binding affinity and necrosis-inducing activity of mutant AVR9 peptide elicitors.

Authors:  M Kooman-Gersmann; R Vogelsang; P Vossen; H W van den Hooven; E Mahé; G Honée; P J de Wit
Journal:  Plant Physiol       Date:  1998-06       Impact factor: 8.340

10.  Human alpha-subunit analogs act as partial agonists to the thyroid-stimulating hormone receptor: differential effects of free and yoked subunits.

Authors:  Krassimira Angelova; Valerie Fremont; Renita Jain; Meng Zhang; David Puett; Prema Narayan; Mariusz W Szkudlinski
Journal:  Endocrine       Date:  2004-06       Impact factor: 3.633
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