Literature DB >> 7581486

Polymorphic forms of the Ah receptor and induction of the CYP1A1 gene.

Y Fujii-Kuriyama1, M Ema, J Mimura, N Matsushita, K Sogawa.   

Abstract

Induction of cytochrome P4501A1 (CYP1A1) by certain xenobiotics is mediated by the Ah receptor/Arnt complex. The present knowledge about the molecular process of induction is summarized with special attention to our recent work on characterization of the polymorphic forms of the Ah receptor.

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Year:  1995        PMID： 7581486     DOI： 10.1097/00008571-199512001-00018

Source DB:  PubMed          Journal:  Pharmacogenetics        ISSN： 0960-314X


  7 in total

1.  Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.

Authors:  Carlo J Milani; Hiroyuki Kobori; John J Mullins; Kenneth D Mitchell
Journal:  Am J Med Sci       Date:  2010-11       Impact factor: 2.378

Review 2.  Molecular basis of polymorphic drug metabolism.

Authors:  A K Daly
Journal:  J Mol Med (Berl)       Date:  1995-11       Impact factor: 4.599

3.  Chronic direct renin inhibition with aliskiren prevents the development of hypertension in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent hypertension.

Authors:  Lily Huang; Catherine G Howard; Kenneth D Mitchell
Journal:  Am J Med Sci       Date:  2012-10       Impact factor: 2.378

4.  Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats.

Authors:  Catherine G Howard; John J Mullins; Kenneth D Mitchell
Journal:  Am J Med Sci       Date:  2010-06       Impact factor: 2.378

5.  Genetic loci that affect aristolochic acid-induced nephrotoxicity in the mouse.

Authors:  Thomas A Rosenquist
Journal:  Am J Physiol Renal Physiol       Date:  2011-03-23

6.  AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.

Authors:  Dustyn E Williams; Minolfa C Prieto; John J Mullins; L Gabriel Navar; Kenneth D Mitchell
Journal:  Am J Med Sci       Date:  2010-04       Impact factor: 2.378

7.  The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells.

Authors:  Maryam Ghotbaddini; Joann B Powell
Journal:  Int J Environ Res Public Health       Date:  2015-07-06       Impact factor: 3.390
  7 in total

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