Literature DB >> 7580896

Quality assurance and use of PCR in clinical trials.

P S Reichelderfer1, J B Jackson.   

Abstract

Qualitative and quantitative HIV-1 DNA and RNA PCR assays are proving to be useful in the diagnosis of HIV-1 infection in infants and in assessing the in vivo antiviral activity of new therapies and regimens in clinical trials. The use of these standardized commercial assays in conjunction with an external quality assurance program has ensured that results from different laboratories are comparable. In addition, real-time proficiency monitoring has the potential to detect problems immediately before patient data are compromised.

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Year:  1994        PMID: 7580896     DOI: 10.1101/gr.4.3.s141

Source DB:  PubMed          Journal:  PCR Methods Appl        ISSN: 1054-9803


  3 in total

1.  Impact of proficiency testing program for laboratories conducting early diagnosis of HIV-1 infection in infants in low- to middle-income countries.

Authors:  Albert Garcia; Shambavi Subbarao; Guoqing Zhang; Linda Parsons; John Nkengasong; Chin-Yih Ou; Dennis Ellenberger
Journal:  J Clin Microbiol       Date:  2013-12-18       Impact factor: 5.948

2.  External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance.

Authors:  Sean C Murphy; Cornelus C Hermsen; Alexander D Douglas; Nick J Edwards; Ines Petersen; Gary A Fahle; Matthew Adams; Andrea A Berry; Zachary P Billman; Sarah C Gilbert; Matthew B Laurens; Odile Leroy; Kristen E Lyke; Christopher V Plowe; Annette M Seilie; Kathleen A Strauss; Karina Teelen; Adrian V S Hill; Robert W Sauerwein
Journal:  PLoS One       Date:  2014-05-16       Impact factor: 3.240

3.  External Quality Assessment Programme for Early Infant Diagnosis of HIV-1, Mozambique, 2011-2014.

Authors:  Nalia Ismael; Orvalho Augusto; Adolfo Vubil; Sofia O Viegas; Fernanda Miambo; Patrina Chongo; Nédio Mabunda
Journal:  Afr J Lab Med       Date:  2018-10-11
  3 in total

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