Literature DB >> 7579202

In-vitro analyses of mechanisms of B-cell development.

A Rolink1, P Ghia, U Grawunder, D Haasner, H Karasuyama, C Kalberer, T Winkler, F Melchers.   

Abstract

B-cell lymphopoiesis in vivo is very complex due to the influences of cooperating cells, cytokines and other receptor-ligand interactions which appear to occur developmentally at different cellular stages. Therefore in-vitro models will help to unravel this complex situation. Here, we review our and others' work on in-vitro models of B-cell development. The role of stromal cells, cytokines, surrogate light chain and products of rearranged Ig-loci in the developmentally different cellular stages will be discussed.

Mesh：

Year:  1995        PMID： 7579202     DOI： 10.1016/1044-5323(95)90043-8

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  7 in total

1.  Fates and potentials of thymus-seeding progenitors.

Authors:  Rhodri Ceredig
Journal:  Nat Immunol       Date:  2012-03-19       Impact factor: 25.606

Review 2.  Checkpoints that control B cell development.

Authors:  Fritz Melchers
Journal:  J Clin Invest       Date:  2015-05-04       Impact factor: 14.808

3.  BCL6 is critical for the development of a diverse primary B cell repertoire.

Authors:  Cihangir Duy; J Jessica Yu; Rahul Nahar; Srividya Swaminathan; Soo-Mi Kweon; Jose M Polo; Ester Valls; Lars Klemm; Seyedmehdi Shojaee; Leandro Cerchietti; Wolfgang Schuh; Hans-Martin Jäck; Christian Hurtz; Parham Ramezani-Rad; Sebastian Herzog; Hassan Jumaa; H Phillip Koeffler; Ignacio Moreno de Alborán; Ari M Melnick; B Hilda Ye; Markus Müschen
Journal:  J Exp Med       Date:  2010-05-24       Impact factor: 14.307

4.  Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.

Authors:  M Askmyr; H Ågerstam; H Lilljebjörn; N Hansen; C Karlsson; S von Palffy; N Landberg; C Högberg; C Lassen; M Rissler; J Richter; M Ehinger; M Järås; T Fioretos
Journal:  Blood Cancer J       Date:  2014-12-12       Impact factor: 11.037

5.  Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance.

Authors:  Sarah A Greaves; Jacob N Peterson; Raul M Torres; Roberta Pelanda
Journal:  Front Immunol       Date:  2018-04-09       Impact factor: 7.561

6.  Active PI3K abrogates central tolerance in high-avidity autoreactive B cells.

Authors:  Sarah A Greaves; Jacob N Peterson; Pamela Strauch; Raul M Torres; Roberta Pelanda
Journal:  J Exp Med       Date:  2019-04-04       Impact factor: 14.307

7.  Regulation of anti-DNA B cells in recombination-activating gene-deficient mice.

Authors:  H Xu; H Li; E Suri-Payer; R R Hardy; M Weigert
Journal:  J Exp Med       Date:  1998-10-05       Impact factor: 14.307
  7 in total

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