Literature DB >> 7577449

Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.

J Vaage1, D Donovan, T Loftus, P Working.   

Abstract

Weekly treatments with doxorubicin encapsulated in long circulating, sterically stabilised liposomes (DOX-SL) reduced the incidence of metastases from primary mammary carcinoma from 24 of 47 untreated mice to 3 of 23 treated mice. Toxic side-effects were limited to minor, transient weight losses.

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Year:  1995        PMID: 7577449      PMCID: PMC2033931          DOI: 10.1038/bjc.1995.467

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  8 in total

1.  Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times.

Authors:  D D Lasic; F J Martin; A Gabizon; S K Huang; D Papahadjopoulos
Journal:  Biochim Biophys Acta       Date:  1991-11-18

2.  Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo.

Authors:  T M Allen; C Hansen; F Martin; C Redemann; A Yau-Young
Journal:  Biochim Biophys Acta       Date:  1991-07-01

3.  Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes.

Authors:  J Vaage; E Mayhew; D Lasic; F Martin
Journal:  Int J Cancer       Date:  1992-07-30       Impact factor: 7.396

4.  Spontaneous metastasis from primary C3H mouse mammary tumors.

Authors:  J Vaage; J P Harlos
Journal:  Cancer Res       Date:  1987-01-15       Impact factor: 12.701

5.  Therapy of mouse mammary carcinomas with vincristine and doxorubicin encapsulated in sterically stabilized liposomes.

Authors:  J Vaage; D Donovan; E Mayhew; P Uster; M Woodle
Journal:  Int J Cancer       Date:  1993-07-30       Impact factor: 7.396

6.  Mammary tumorigenesis and tumor morphology in four C3H sublines with or without exogenous mammary tumor virus.

Authors:  J Vaage; G H Smith; B B Asch; Y Teramoto
Journal:  Cancer Res       Date:  1986-04       Impact factor: 12.701

7.  Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

Authors:  A Gabizon; D Papahadjopoulos
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

8.  Tissue distribution and therapeutic effect of intravenous free or encapsulated liposomal doxorubicin on human prostate carcinoma xenografts.

Authors:  J Vaage; E Barberá-Guillem; R Abra; A Huang; P Working
Journal:  Cancer       Date:  1994-03-01       Impact factor: 6.860

  8 in total
  3 in total

Review 1.  Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS-related Kaposi's sarcoma.

Authors:  Miriam Sharpe; Stephanie E Easthope; Gillian M Keating; Harriet M Lamb
Journal:  Drugs       Date:  2002       Impact factor: 9.546

2.  Biodistribution and pharmacokinetics of 111In-DTPA-labelled pegylated liposomes in a human tumour xenograft model: implications for novel targeting strategies.

Authors:  K J Harrington; G Rowlinson-Busza; K N Syrigos; P S Uster; R M Abra; J S Stewart
Journal:  Br J Cancer       Date:  2000-07       Impact factor: 7.640

3.  Psychosocial stress augments tumor development through beta-adrenergic activation in mice.

Authors:  Hideo Hasegawa; Ikuo Saiki
Journal:  Jpn J Cancer Res       Date:  2002-07
  3 in total

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