Literature DB >> 7576346

Understanding the causes of aging and cancer.

B N Ames1.   

Abstract

Cancer, a disease typical of old age, is in large part of degenerative origin. Several factors leading to the development of cancer and other degenerative diseases are discussed. The results of cancer tests in animals have been misinterpreted; they are mainly carried out by using synthetic chemicals, whereas most carcinogenic substances are natural chemicals. Animals have defense systems which prevent them from the carcinogenic effects of both natural and synthetic chemicals.

Entities:  

Mesh:

Year:  1995        PMID: 7576346

Source DB:  PubMed          Journal:  Microbiologia        ISSN: 0213-4101


  3 in total

1.  A continuous hyperchromicity assay to characterize the kinetics and thermodynamics of DNA lesion recognition and base excision.

Authors:  Conceição A S A Minetti; David P Remeta; Kenneth J Breslauer
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-02       Impact factor: 11.205

2.  Multi-organ characterization of mitochondrial genomic rearrangements in ad libitum and caloric restricted mice show striking somatic mitochondrial DNA rearrangements with age.

Authors:  S Melov; D Hinerfeld; L Esposito; D C Wallace
Journal:  Nucleic Acids Res       Date:  1997-03-01       Impact factor: 16.971

3.  Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps.

Authors:  A Martinez; R Kolter
Journal:  J Bacteriol       Date:  1997-08       Impact factor: 3.490

  3 in total

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