Literature DB >> 7575763

[The Candida infected hen's egg. An alternative test system for systemic anticandida activity].

A Härtl1, H G Hillesheim, W Künkel, E J Schrinner.   

Abstract

The Candida infected, embryonated hen's egg is a realistic complement for the model of the Candida infected mouse and can be used in the search for new systemically active antimycotics. This alternative method is rapid, sensitive convincing and inexpensive. The use of the embryonated hen's egg in an anti-Candida screening can reduce the use of small laboratory animals to a considerable amount. Thus, with the help of this new method pain and suffering of animals can be reduced in a part of the biologic-medical research in the sense of the animal protection law.

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Year:  1995        PMID: 7575763

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  4 in total

1.  Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence.

Authors:  Ilse D Jacobsen; Katharina Grosse; Silvia Slesiona; Bernhard Hube; Angela Berndt; Matthias Brock
Journal:  Infect Immun       Date:  2010-04-26       Impact factor: 3.441

2.  Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans.

Authors:  François L Mayer; Duncan Wilson; Ilse D Jacobsen; Pedro Miramón; Silvia Slesiona; Iryna M Bohovych; Alistair J P Brown; Bernhard Hube
Journal:  PLoS One       Date:  2012-06-07       Impact factor: 3.240

3.  Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections.

Authors:  Ilse D Jacobsen; Katharina Grosse; Angela Berndt; Bernhard Hube
Journal:  PLoS One       Date:  2011-05-13       Impact factor: 3.240

4.  Lichtheimia species exhibit differences in virulence potential.

Authors:  Volker U Schwartze; Kerstin Hoffmann; Ildikó Nyilasi; Tamás Papp; Csaba Vágvölgyi; Sybren de Hoog; Kerstin Voigt; Ilse D Jacobsen
Journal:  PLoS One       Date:  2012-07-20       Impact factor: 3.240

  4 in total

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