Literature DB >> 7574943

CABG in octogenarians: early and late events and actuarial survival in comparison with a matched population.

M E Cane1, C Chen, B M Bailey, J Fernandez, G W Laub, W A Anderson, L B McGrath.   

Abstract

BACKGROUND: With important demographic changes in cardiac surgical practice, more older patients are undergoing complex cardiac operations. Controversy exists as to whether the expenditure of healthcare resources on the growing elderly populations represents an effective approach in maintaining a meaningful quality of life.
METHODS: From January 1982 through April 1991, 121 consecutive octogenarians underwent a surgical procedure that included coronary artery bypass grafting. Retrospective review of patient medical records was performed; follow-up information was obtained via telephone contact with the patient, the patient's family, or the patient's physician.
RESULTS: There were 67 men (55%) and 54 women (45%). Mean age was 82.1 years (range, 80 to 89 years). Sixty-nine percent of the patients were having class III or IV symptoms. There were 11 hospital deaths (9.1%); risk factors included longer cardiopulmonary bypass time (p = 0.01), higher preoperative left ventricular end-diastolic pressure (p = 0.02), advanced age (p = 0.05), history of renal disease (p = 0.02), and myocardial infarction (p = 0.04). Late death occurred in 34 patients (30.9%) at a mean of 27 months postoperatively; univariate risk factors included chronic obstructive pulmonary disease (p = 0.009), higher left-ventricular end-diastolic pressure (p = 0.03), and recent myocardial infarction (p = 0.03). Actuarial survival, including hospital death, was 32.8% at 80 months, compared with 37.6% for an age; sex; and race-matched population (p > 0.3). Most late survivors (84%) were in New York Heart Association class I or II.
CONCLUSIONS: We conclude that coronary artery bypass grafting can be performed in octogenarians with an acceptable, although increased risk. Hospital survivors have a good late functional status but are at risk for pulmonary and other atherosclerosis-related events, which impair overall survival.

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Year:  1995        PMID: 7574943     DOI: 10.1016/0003-4975(95)00429-o

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  14 in total

1.  Equity in access to exercise tolerance testing, coronary angiography, and coronary artery bypass grafting by age, sex and clinical indications.

Authors:  A Bowling; M Bond; D McKee; M McClay; A P Banning; N Dudley; A Elder; A Martin; I Blackman
Journal:  Heart       Date:  2001-06       Impact factor: 5.994

2.  Higher age predicts adverse outcome and readmission after coronary artery bypass grafting.

Authors:  Otso Järvinen; Heini Huhtala; Jari Laurikka; Matti R Tarkka
Journal:  World J Surg       Date:  2003-11-05       Impact factor: 3.352

3.  Cardiac surgery in patients aged 80 years and older.

Authors:  Masashi Tanaka; Koji Kawahito; Hideo Adachi; Atsushi Yamaguchi; Takashi Ino
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2002-12

Review 4.  Advanced neurologic monitoring for cardiac surgery.

Authors:  Alexander Y Razumovsky; Lavern D Gugino; Jeffrey H Owen
Journal:  Curr Cardiol Rep       Date:  2006-02       Impact factor: 2.931

5.  Cardio-aortic operation in octogenarians.

Authors:  M Ohashi; S Fukunaga; H Kawano; E Tayama; H Kashikie; H Akashi; T Kawara; A Ohryoji; S Aoyagi
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2001-01

6.  Perioperative features of coronary artery bypass grafting in patients aged 75 years or older.

Authors:  Toshiro Kobayashi; Kimikazu Hamano; Akihito Mikamo; Haruhiko Okada; Hidenori Gohra; Masaki Miyamoto; Tatsuro Oda; Kensuke Esato
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2002-04

7.  Psychological status and the role of coping style after coronary artery bypass graft surgery. Results of a prospective study.

Authors:  H Boudrez; G De Backer
Journal:  Qual Life Res       Date:  2001       Impact factor: 4.147

8.  Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: Intervention in Older Persons with Acute Coronary Syndrome-Part II.

Authors:  Brett C Sheridan; Sally C Stearns; Mark W Massing; George A Stouffer; Laura P D'Arcy; Timothy S Carey
Journal:  Clin Geriatr       Date:  2008-11

Review 9.  [Arterial myocardial revascularization in the 9th decade of life. Personal results and review of the literature].

Authors:  A Mortasawi; I C Ennker; A Albert; U Rosendahl; F Dalladaku; T Alexander; J Ennker
Journal:  Herz       Date:  1999-04       Impact factor: 1.443

10.  [Ischemic preconditioning in the aged heart--myocardial protective effect as compared with the mature heart].

Authors:  M Uematsu; M Okada
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  1998-09
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