Literature DB >> 7573701

Detection of hepatitis E virus infections among domestic swine in the Kathmandu Valley of Nepal.

E T Clayson1, B L Innis, K S Myint, S Narupiti, D W Vaughn, S Giri, P Ranabhat, M P Shrestha.   

Abstract

The prevalence of hepatitis E virus (HEV) infections among 55 domestic swine living in the Kathmandu Valley of Nepal was investigated. Sera and stool specimens were collected from 47 free-roaming swine and examined for the presence of HEV genomic sequences by the reverse transcription-polymerase chain reaction. Sera from these animals, as well as sera from eight other swine, were also examined for the presence of HEV-specific antibodies by an enzyme-linked immunosorbent assay and by a fluorescent antibody blocking assay. Hepatitis E virus RNA was detected in the sera and/or stool of three of 47 swine, while HEV-specific antibodies were detected in 18 of 55 swine. These results indicate that HEV is a zoonotic virus, and that swine are among its natural hosts.

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Year:  1995        PMID： 7573701     DOI： 10.4269/ajtmh.1995.53.228

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  33 in total

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