| Literature DB >> 7573261 |
O Bardicef1, M Bardicef, Y Sorokin, D B Cotton, L M Resnick.
Abstract
To investigate acid-base homeostasis in pregnancy, we used phosphorus 31 nuclear magnetic resonance spectroscopy to measure intracellular pH in erythrocytes from nonpregnant (n = 33) and third-trimester pregnant women (n = 22). Intracellular pH was lower in pregnant compared with nonpregnant controls (7.23 +/- 0.015 vs 7.29 +/- 0.012, p = 0.003). We hypothesize that this "physiologic" intracellular acidosis of pregnancy potentiates oxygen-hemoglobin dissociation and oxygen delivery across the placenta.Entities:
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Year: 1995 PMID： 7573261 DOI： 10.1016/0002-9378(95)90358-5
Source DB: PubMed Journal: Am J Obstet Gynecol ISSN： 0002-9378 Impact factor: 8.661