| Literature DB >> 7571353 |
K McEntee1, M Grauwels, C Clercx, M Henroteaux.
Abstract
A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial deafness, hepatotoxicosis and myopathy. Only the blindness was irreversible. The therapy included albumin administration to reduce the acute toxicity of closantel.Entities:
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Year: 1995 PMID： 7571353
Source DB: PubMed Journal: Vet Hum Toxicol ISSN： 0145-6296