Literature DB >> 7570673

The expanding role of quantitative structure-activity relationships (QSAR) in toxicology.

C Hansch1, D Hoekman, A Leo, L Zhang, P Li.   

Abstract

Quantitative structure-activity relationships (QSAR) have found wide use in correlating the bioactivity of all kinds of organic compounds with all kinds of biological entities. So many QSAR have been published that it is time for a new phase of study, that of comparative QSAR. From our current database of about 6000 QSAR illustrative examples are discussed.

Mesh:

Year:  1995        PMID: 7570673     DOI: 10.1016/0378-4274(95)03356-p

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  23 in total

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6.  Continuous steady-state method using tenax for delivering tetrachloroethene to chloro-respiring bacteria.

Authors:  Rachel A Brennan; Robert A Sanford
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Review 8.  Adaptation of high-throughput screening in drug discovery-toxicological screening tests.

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9.  A novel approach for a toxicity prediction model of environmental pollutants by using a quantitative structure-activity relationship method based on toxicogenomics.

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10.  Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.

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