T Wiegel1, M Kleineidam, A Schilling. 1. Abteilung für Strahlentherapie, Klinikum Benjamin Franklin, Freie Universität Berlin.
Abstract
PURPOSE: Choroidal metastasis from other primaries than breast cancer or lung cancer is a rare event. There is no documented case in the literature of a choroid metastasis in a patient with adenocarcinoma of the uterine cervix. PATIENT AND METHOD: The case of a pregnant 25-year-old woman with cervix carcinoma (stage FIGO Ib) is presented. Following abortion and radical surgery no additional treatment was performed. Two years later the patient developed the signs of retinal detachment and a partial visus lost in her left eye. A solitary choroidal metastasis in the left eye was diagnosed by an ophthalmologist. The additional CT of the lung showed pulmonary metastases. Histological examination of a biopsy revealed lung metastases from the cervix carcinoma. RESULTS: The choroid was irradiated up to a total dose of 40 Gy, 5 times a week with a single dose of 2 Gy. Then an additional chemotherapy was performed. Within the time of radiotherapy a relief of the symptom was obtained. Eight weeks after the end of radiotherapy there was no detectable tumor any more in the left eye (complete remission). CONCLUSIONS: The case illustrates the importance of rapidly responding to ophthalmologic complications in patients with cancer in general. Radiotherapy is a very effective treatment in reducing ophthalmologic symptoms in the case of choroidal metastases.
PURPOSE: Choroidal metastasis from other primaries than breast cancer or lung cancer is a rare event. There is no documented case in the literature of a choroid metastasis in a patient with adenocarcinoma of the uterine cervix. PATIENT AND METHOD: The case of a pregnant 25-year-old woman with cervix carcinoma (stage FIGO Ib) is presented. Following abortion and radical surgery no additional treatment was performed. Two years later the patient developed the signs of retinal detachment and a partial visus lost in her left eye. A solitary choroidal metastasis in the left eye was diagnosed by an ophthalmologist. The additional CT of the lung showed pulmonary metastases. Histological examination of a biopsy revealed lung metastases from the cervix carcinoma. RESULTS: The choroid was irradiated up to a total dose of 40 Gy, 5 times a week with a single dose of 2 Gy. Then an additional chemotherapy was performed. Within the time of radiotherapy a relief of the symptom was obtained. Eight weeks after the end of radiotherapy there was no detectable tumor any more in the left eye (complete remission). CONCLUSIONS: The case illustrates the importance of rapidly responding to ophthalmologic complications in patients with cancer in general. Radiotherapy is a very effective treatment in reducing ophthalmologic symptoms in the case of choroidal metastases.
Authors: Akshay Gopinathan Nair; Haresh T Asnani; Vinod C Mehta; Siddharth V Mehta; Rima S Pathak Journal: Indian J Ophthalmol Date: 2015-08 Impact factor: 1.848