BACKGROUND: Reticular pseudodrusen refer to a yellow interlacing network 125 microns to 250 microns wide appearing first in the superior outer macula and then extending circumferentially and beyond. Unlike true drusen, they do not fluoresce on fluorescein or indocyanine green angiography, and are best seen in red-free light or with the He-Ne laser of the scanning laser ophthalmoscope. METHODS: One hundred patients have been seen in our retinal practice with this clinical feature in the past 3 years. RESULTS: All had some manifestation of age-related maculopathy (ARM), and 66% had or subsequently developed subretinal new vessels in one or both eyes. The appearance is attributed to changes in the choroid. CONCLUSIONS: Reticular pseudodrusen are an easily recognizable clinical sign, and may be an important risk factor for choroidal neovascularization in ARM.
BACKGROUND: Reticular pseudodrusen refer to a yellow interlacing network 125 microns to 250 microns wide appearing first in the superior outer macula and then extending circumferentially and beyond. Unlike true drusen, they do not fluoresce on fluorescein or indocyanine green angiography, and are best seen in red-free light or with the He-Ne laser of the scanning laser ophthalmoscope. METHODS: One hundred patients have been seen in our retinal practice with this clinical feature in the past 3 years. RESULTS: All had some manifestation of age-related maculopathy (ARM), and 66% had or subsequently developed subretinal new vessels in one or both eyes. The appearance is attributed to changes in the choroid. CONCLUSIONS: Reticular pseudodrusen are an easily recognizable clinical sign, and may be an important risk factor for choroidal neovascularization in ARM.
Authors: Patrick A Kaszubski; Tal Ben Ami; Céline Saade; Camellia Nabati; Vivek Kumar; Ana Rita Santos; Rufino Silva; Maria Luz Cachulo; José G Cunha-Vaz; R Theodore Smith Journal: Int Ophthalmol Date: 2017-03-07 Impact factor: 2.031
Authors: Ronald Klein; Stacy M Meuer; Michael D Knudtson; Sudha K Iyengar; Barbara E K Klein Journal: Am J Ophthalmol Date: 2007-11-28 Impact factor: 5.258
Authors: Abbas Shirinifard; James Alexander Glazier; Maciej Swat; J Scott Gens; Fereydoon Family; Yi Jiang; Hans E Grossniklaus Journal: PLoS Comput Biol Date: 2012-05-03 Impact factor: 4.475
Authors: S Scott Whitmore; Elliott H Sohn; Kathleen R Chirco; Arlene V Drack; Edwin M Stone; Budd A Tucker; Robert F Mullins Journal: Prog Retin Eye Res Date: 2014-12-05 Impact factor: 21.198