| Literature DB >> 7568178 |
M A Guedeau-Boudeville1, L Jullien, J M di Meglio.
Abstract
Experimental evidence is presented that supports the possibility of building a "molecular drill." By the adsorption of a vesicle onto a porous substrate (specifically, a lycopode grain), it was possible to increase the permeability of the vesicle by locally stretching its membrane. Molecules contained within the vesicle, which could not cross the membrane, were delivered to the porous substrate upon adsorption. This general process could provide another method for drug delivery and targeting.Entities:
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Year: 1995 PMID： 7568178 PMCID： PMC40847 DOI： 10.1073/pnas.92.21.9590
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205