| Literature DB >> 7567911 |
R P McMaster1, J E Huffman, B Fried.
Abstract
Golden hamsters (Mesocricetus auratus) were given intramuscular injections of dexamethasone and infected with Echinostoma caproni or E. trivolvis. All animals were necropsied on day 14 postinfection. Dexamethasone treatment at high doses resulted in increased parasite recovery. Decreased total white blood cell counts and decreased relative splenic weights were observed in corticosteroid-treated hamsters. Dexamethasone-treated animals also demonstrated significantly lower mean parasite dry weights for E. caproni. Specific serum IgG against the parasites was not detected in corticosteroid-treated hamsters on day 14 postinfection.Entities:
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Year: 1995 PMID: 7567911 DOI: 10.1007/BF00931795
Source DB: PubMed Journal: Parasitol Res ISSN: 0932-0113 Impact factor: 2.289