| Literature DB >> 7566096 |
I M Chumakov1, P Rigault, I Le Gall, C Bellanné-Chantelot, A Billault, S Guillou, P Soularue, G Guasconi, E Poullier, I Gros.
Abstract
A yeast artificial chromosome library containing 33,000 clones with an average insert size of one megabase of human genomic DNA was extensively analysed by several different procedures for detecting overlaps and positional information. We developed an analysis strategy that resulted, after confirmatory tests, in a YAC contig map reliably covering about 75% of the human genome in 225 contigs having an average size of about ten megabases.Entities:
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Year: 1995 PMID: 7566096 DOI: 10.1038/377175a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962