Literature DB >> 7565438

Parathyroid hormone-related peptide expression in endocrine tumors.

S Nagataki1, M Nakashima, K Akino, A Ohtsuru, H Namba, T Kiriyama, M Ito, I Sekine, S Yamashita.   

Abstract

Parathyroid hormone-related peptide (PTHrP) expression is associated with the histological type in pituitary tumor, but not in thyroid carcinoma. However invasive and metastatic tumors showed intense PTHrP staining in both pituitary and thyroid tumors. Analysis of the established metastatic rat pituitary tumor cell line showed that PTHrP plays a crucial role in in vivo cell proliferation closely related to worsening of malignant transformation and neovascularization in a paracrine fashion.

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Year:  1995        PMID: 7565438

Source DB:  PubMed          Journal:  Miner Electrolyte Metab        ISSN: 0378-0392


  2 in total

1.  Undetectable inferior petrosal sinus levels of PTH-related peptide (PTHrP) in patients with ACTH-dependent Cushing's disease.

Authors:  L Manetti; L Grasso; C Vignali; P Petruzzi; I Lupi; M Genovesi; L L Morselli; F Cetani; G Acerbi; E Martino
Journal:  J Endocrinol Invest       Date:  2005-10       Impact factor: 4.256

Review 2.  Parathyroid-hormone-related peptides. A new class of multifunctional proteins.

Authors:  T Roskams; V Desmet
Journal:  Am J Pathol       Date:  1997-03       Impact factor: 4.307

  2 in total

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