PURPOSE: The development of a thrombus extending into the veins is well recognized in renal cell carcinoma. We investigated the hypothesis that vein invasion alone has no adverse impact on survival but is a highly negative factor in other tumors. MATERIALS AND METHODS: In 200 consecutive patients invasion of the renal vein and vena cava was evaluated and compared with the clinical course. RESULTS: A total of 26 patients had vena caval and 47 had renal vein invasion. Patients with venous invasion had a significantly shorter survival but no survival difference was demonstrated based on the level of involvement. CONCLUSIONS: Our study indicates that vein invasion itself seems to be an important prognostic factor in renal cell carcinoma.
PURPOSE: The development of a thrombus extending into the veins is well recognized in renal cell carcinoma. We investigated the hypothesis that vein invasion alone has no adverse impact on survival but is a highly negative factor in other tumors. MATERIALS AND METHODS: In 200 consecutive patients invasion of the renal vein and vena cava was evaluated and compared with the clinical course. RESULTS: A total of 26 patients had vena caval and 47 had renal vein invasion. Patients with venous invasion had a significantly shorter survival but no survival difference was demonstrated based on the level of involvement. CONCLUSIONS: Our study indicates that vein invasion itself seems to be an important prognostic factor in renal cell carcinoma.
Authors: Andreas M Hötker; Christoph A Karlo; Junting Zheng; Chaya S Moskowitz; Paul Russo; Hedvig Hricak; Oguz Akin Journal: AJR Am J Roentgenol Date: 2016-03-02 Impact factor: 3.959
Authors: Wei Xing; Xiaozhou He; Mohammad A Kassir; Jie Chen; Jiule Ding; Jun Sun; Jiani Hu; Zishu Zhang; E Mark Haacke; Yongming Dai Journal: PLoS One Date: 2013-02-25 Impact factor: 3.240